STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lolDLipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (232 aa)    
Predicted Functional Partners:
Lcho_2398
TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: mpt:Mpe_A2748 putative lipoprotein releasing system transmembrane.
 
 0.989
Lcho_4267
PFAM: protein of unknown function DUF214; KEGG: mpt:Mpe_A2068 hypothetical protein.
  
 
 0.984
Lcho_3709
PFAM: protein of unknown function DUF214; KEGG: dar:Daro_3916 protein of unknown function DUF214.
 
 0.960
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
 
 
 0.725
lolA
Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
   
 
 0.716
rpsE
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
  
   
 0.668
Lcho_1282
PFAM: protein of unknown function DUF214; KEGG: mpt:Mpe_A2047 ABC transporter, permease protein.
  
 
 0.650
Lcho_1262
ABC transporter-related protein; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_3238 ABC transporter related.
   
0.642
Lcho_2400
TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mpt:Mpe_A2751 putative single-stranded-DNA-specific exonuclease.
  
    0.640
Lcho_3557
PFAM: protein of unknown function DUF214; KEGG: mpt:Mpe_A1825 hypothetical protein.
  
 
 0.634
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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