STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_2441PFAM: thiamineS protein; KEGG: ade:Adeh_2222 thiamineS. (89 aa)    
Predicted Functional Partners:
Lcho_2020
PFAM: molybdopterin biosynthesis MoaE protein; KEGG: aav:Aave_1248 molybdopterin biosynthesis MoaE.
  
 0.995
Lcho_2100
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: mpt:Mpe_A1083 putative molybdopterin biosynthesis protein.
  
 0.971
Lcho_2021
TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: mpt:Mpe_A1545 molybdopterin converting factor subunit 1.
     
  0.900
Lcho_2440
KEGG: mpt:Mpe_A3522 hypothetical protein.
 
    0.892
Lcho_0491
TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; KEGG: mpt:Mpe_A0062 molybdenum cofactor biosynthesis protein.
  
  
 0.849
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
   
 
 0.706
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
  
 0.603
Lcho_1221
TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; KEGG: mpt:Mpe_A2838 molybdopterin biosynthesis Mog protein.
 
  
 0.592
Lcho_2442
Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
     
 0.566
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
    0.560
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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