STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_2482Hypothetical protein; KEGG: lme:LEUM_1946 trypsin-like serine protease with PDZ domain. (485 aa)    
Predicted Functional Partners:
Lcho_2483
Hypothetical protein.
       0.788
Lcho_2484
KEGG: pol:Bpro_3104 galactarate dehydratase; TIGRFAM: galactarate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein.
       0.608
Lcho_0604
PFAM: Anti sigma-E protein RseA family protein; KEGG: mpt:Mpe_A0643 putative transmembrane sigma-E factor negative regulatory transcription regulator protein.
  
 
 0.549
Lcho_0640
KEGG: sde:Sde_2125 4-alpha-L-fucosyltransferase.
   
 0.477
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.477
Lcho_1449
PAS/PAC sensor hybrid histidine kinase; KEGG: dar:Daro_2934 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
  
 0.458
Lcho_4210
Multi-sensor hybrid histidine kinase; KEGG: dar:Daro_3006 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; SMART: PAS domain containing protein.
  
  
 0.435
Lcho_4096
Histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: mpt:Mpe_A1150 signal transduction histidine kinase-like protein.
  
  
 0.433
Lcho_2882
Phage shock protein C, PspC; PFAM: PspC domain protein; KEGG: sat:SYN_00293 transcriptional regulator-like protein.
  
  
 0.424
Lcho_4069
PAS/PAC sensor hybrid histidine kinase; KEGG: azo:azo2482 putative hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
  
 0.401
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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