STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_2497TIGRFAM: thymidine phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; KEGG: rfr:Rfer_2241 thymidine phosphorylase. (509 aa)    
Predicted Functional Partners:
Lcho_2496
KEGG: psa:PST_0859 ribose-phosphate pyrophosphokinase family protein; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family.
 
   
 0.955
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.947
upp-2
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.947
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.932
Lcho_0318
N-isopropylammelide isopropylaminohydrolase; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: rso:RSc1594 cytosine deaminase.
    
 0.921
Lcho_3960
PFAM: phosphoribosyltransferase; KEGG: mpt:Mpe_A0707 bifunctional regulator/uracil phosphoribosyltransferase.
     
 0.918
ppnP
Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
 0.913
Lcho_3013
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: rpa:RPA0955 putative 5'-nucleotidase family protein; Belongs to the 5'-nucleotidase family.
    
 0.906
Lcho_3214
PFAM: 5'-Nucleotidase domain protein; KEGG: sde:Sde_0580 alkaline phosphatase; Belongs to the 5'-nucleotidase family.
    
 0.906
Lcho_2486
PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: tbd:Tbd_0095 metallo-beta-lactamase superfamily protein.
    0.729
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.