STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_2500PFAM: protein of unknown function DUF485; KEGG: pnu:Pnuc_0534 protein of unknown function DUF485. (102 aa)    
Predicted Functional Partners:
Lcho_2501
TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: pnu:Pnuc_0535 SSS sodium solute transporter superfamily; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.991
Lcho_2504
PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294 nucleotidyltransferase putative; KEGG: pna:Pnap_0480 cyclic nucleotide-binding protein.
 
  
 0.875
Lcho_2831
PFAM: Na+/solute symporter; KEGG: mpt:Mpe_A0866 putative membrane transport protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.870
Lcho_2503
PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: pna:Pnap_0481 exonuclease, RNase T and DNA polymerase III.
 
    0.827
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
    0.610
Lcho_2691
TIGRFAM: propionate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: rfr:Rfer_2322 propionate--CoA ligase.
  
  
 0.519
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.519
Lcho_3655
TIGRFAM: benzoate-CoA ligase family; PFAM: AMP-dependent synthetase and ligase; KEGG: rfr:Rfer_0216 benzoate-CoA ligase family.
  
  
 0.519
Lcho_2502
Multi-sensor hybrid histidine kinase; KEGG: dar:Daro_2754 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
       0.477
Lcho_2498
KEGG: mpt:Mpe_A1032 general secretion pathway protein B.
       0.455
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.