STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_2526PFAM: MscS Mechanosensitive ion channel; KEGG: mpt:Mpe_A0411 putative transmembrane protein. (272 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
    0.610
Lcho_0181
Sodium/hydrogen exchanger; PFAM: TrkA-N domain protein; TrkA-C domain protein; sodium/hydrogen exchanger; KEGG: mpt:Mpe_A3810 sodium/hydrogen exchanger family protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.522
Lcho_3066
PFAM: MscS Mechanosensitive ion channel; KEGG: pol:Bpro_3144 MscS mechanosensitive ion channel.
 
  
 0.500
Lcho_2524
Hypothetical protein.
       0.485
Lcho_2525
Hypothetical protein.
       0.485
Lcho_3853
PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: pna:Pnap_0633 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.465
Lcho_4069
PAS/PAC sensor hybrid histidine kinase; KEGG: azo:azo2482 putative hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
     
 0.465
Lcho_1296
TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: pol:Bpro_1237 glutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.461
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.442
Lcho_2097
TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: mpt:Mpe_A1880 outer membrane protein.
 
     0.437
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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