node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lcho_1664 | Lcho_3179 | Lcho_1664 | Lcho_3179 | KEGG: mpt:Mpe_A2461 putative ATP-dependent clp protease ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: eba:ebA3490 hypothetical protein. | 0.636 |
Lcho_1664 | Lcho_3374 | Lcho_1664 | Lcho_3374 | KEGG: mpt:Mpe_A2461 putative ATP-dependent clp protease ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: tbd:Tbd_1431 putative heat shock protein, DnaJ family. | 0.646 |
Lcho_1664 | dnaJ | Lcho_1664 | Lcho_2577 | KEGG: mpt:Mpe_A2461 putative ATP-dependent clp protease ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.636 |
Lcho_1664 | dnaK | Lcho_1664 | Lcho_2576 | KEGG: mpt:Mpe_A2461 putative ATP-dependent clp protease ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.759 |
Lcho_1664 | groL | Lcho_1664 | Lcho_0483 | KEGG: mpt:Mpe_A2461 putative ATP-dependent clp protease ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.587 |
Lcho_1664 | groS | Lcho_1664 | Lcho_0482 | KEGG: mpt:Mpe_A2461 putative ATP-dependent clp protease ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.592 |
Lcho_1664 | grpE | Lcho_1664 | Lcho_2575 | KEGG: mpt:Mpe_A2461 putative ATP-dependent clp protease ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.722 |
Lcho_1664 | htpG | Lcho_1664 | Lcho_0551 | KEGG: mpt:Mpe_A2461 putative ATP-dependent clp protease ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.635 |
Lcho_3179 | Lcho_1664 | Lcho_3179 | Lcho_1664 | PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: eba:ebA3490 hypothetical protein. | KEGG: mpt:Mpe_A2461 putative ATP-dependent clp protease ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.636 |
Lcho_3179 | Lcho_3374 | Lcho_3179 | Lcho_3374 | PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: eba:ebA3490 hypothetical protein. | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: tbd:Tbd_1431 putative heat shock protein, DnaJ family. | 0.653 |
Lcho_3179 | Lcho_4084 | Lcho_3179 | Lcho_4084 | PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: eba:ebA3490 hypothetical protein. | Type VI secretion ATPase, ClpV1 family; KEGG: azo:azo3903 putative ATP-dependent Clp protease, ATP-binding subunit ClpB; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.633 |
Lcho_3179 | clpB | Lcho_3179 | Lcho_2019 | PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: eba:ebA3490 hypothetical protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.633 |
Lcho_3179 | dnaK | Lcho_3179 | Lcho_2576 | PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: eba:ebA3490 hypothetical protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.951 |
Lcho_3179 | groL | Lcho_3179 | Lcho_0483 | PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: eba:ebA3490 hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.791 |
Lcho_3179 | groS | Lcho_3179 | Lcho_0482 | PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: eba:ebA3490 hypothetical protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.631 |
Lcho_3179 | grpE | Lcho_3179 | Lcho_2575 | PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: eba:ebA3490 hypothetical protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.888 |
Lcho_3179 | htpG | Lcho_3179 | Lcho_0551 | PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: eba:ebA3490 hypothetical protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.929 |
Lcho_3374 | Lcho_1664 | Lcho_3374 | Lcho_1664 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: tbd:Tbd_1431 putative heat shock protein, DnaJ family. | KEGG: mpt:Mpe_A2461 putative ATP-dependent clp protease ATP-binding subunit; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.646 |
Lcho_3374 | Lcho_3179 | Lcho_3374 | Lcho_3179 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: tbd:Tbd_1431 putative heat shock protein, DnaJ family. | PFAM: DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: eba:ebA3490 hypothetical protein. | 0.653 |
Lcho_3374 | Lcho_4084 | Lcho_3374 | Lcho_4084 | PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: tbd:Tbd_1431 putative heat shock protein, DnaJ family. | Type VI secretion ATPase, ClpV1 family; KEGG: azo:azo3903 putative ATP-dependent Clp protease, ATP-binding subunit ClpB; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.646 |