node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lcho_0086 | Lcho_0329 | Lcho_0086 | Lcho_0329 | KEGG: pol:Bpro_0661 D-serine deaminase. | KEGG: mpt:Mpe_A1429 L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.902 |
Lcho_0086 | Lcho_1989 | Lcho_0086 | Lcho_1989 | KEGG: pol:Bpro_0661 D-serine deaminase. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pna:Pnap_1622 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | 0.809 |
Lcho_0086 | Lcho_2692 | Lcho_0086 | Lcho_2692 | KEGG: pol:Bpro_0661 D-serine deaminase. | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mpt:Mpe_A1018 lactoylglutathione lyase. | 0.806 |
Lcho_0086 | Lcho_2915 | Lcho_0086 | Lcho_2915 | KEGG: pol:Bpro_0661 D-serine deaminase. | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.806 |
Lcho_0086 | Lcho_4179 | Lcho_0086 | Lcho_4179 | KEGG: pol:Bpro_0661 D-serine deaminase. | PFAM: 6-phosphogluconate dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mpt:Mpe_A0213 putative 2-hydroxyacid dehydrogenase in PhoH-CsgG intergenic region. | 0.800 |
Lcho_0086 | ilvA | Lcho_0086 | Lcho_3416 | KEGG: pol:Bpro_0661 D-serine deaminase. | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.918 |
Lcho_0329 | Lcho_0086 | Lcho_0329 | Lcho_0086 | KEGG: mpt:Mpe_A1429 L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | KEGG: pol:Bpro_0661 D-serine deaminase. | 0.902 |
Lcho_0329 | Lcho_1989 | Lcho_0329 | Lcho_1989 | KEGG: mpt:Mpe_A1429 L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pna:Pnap_1622 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | 0.820 |
Lcho_0329 | Lcho_2692 | Lcho_0329 | Lcho_2692 | KEGG: mpt:Mpe_A1429 L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mpt:Mpe_A1018 lactoylglutathione lyase. | 0.800 |
Lcho_0329 | Lcho_2915 | Lcho_0329 | Lcho_2915 | KEGG: mpt:Mpe_A1429 L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.800 |
Lcho_0329 | Lcho_4179 | Lcho_0329 | Lcho_4179 | KEGG: mpt:Mpe_A1429 L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | PFAM: 6-phosphogluconate dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mpt:Mpe_A0213 putative 2-hydroxyacid dehydrogenase in PhoH-CsgG intergenic region. | 0.802 |
Lcho_0329 | ilvA | Lcho_0329 | Lcho_3416 | KEGG: mpt:Mpe_A1429 L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.941 |
Lcho_0329 | trpB | Lcho_0329 | Lcho_1682 | KEGG: mpt:Mpe_A1429 L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
Lcho_1418 | Lcho_1989 | Lcho_1418 | Lcho_1989 | PFAM: amine oxidase; KEGG: azc:AZC_3405 flavin-containing protein. | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pna:Pnap_1622 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | 0.803 |
Lcho_1418 | Lcho_2692 | Lcho_1418 | Lcho_2692 | PFAM: amine oxidase; KEGG: azc:AZC_3405 flavin-containing protein. | PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mpt:Mpe_A1018 lactoylglutathione lyase. | 0.802 |
Lcho_1418 | Lcho_2915 | Lcho_1418 | Lcho_2915 | PFAM: amine oxidase; KEGG: azc:AZC_3405 flavin-containing protein. | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.802 |
Lcho_1418 | Lcho_4179 | Lcho_1418 | Lcho_4179 | PFAM: amine oxidase; KEGG: azc:AZC_3405 flavin-containing protein. | PFAM: 6-phosphogluconate dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mpt:Mpe_A0213 putative 2-hydroxyacid dehydrogenase in PhoH-CsgG intergenic region. | 0.866 |
Lcho_1989 | Lcho_0086 | Lcho_1989 | Lcho_0086 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pna:Pnap_1622 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | KEGG: pol:Bpro_0661 D-serine deaminase. | 0.809 |
Lcho_1989 | Lcho_0329 | Lcho_1989 | Lcho_0329 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pna:Pnap_1622 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | KEGG: mpt:Mpe_A1429 L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.820 |
Lcho_1989 | Lcho_1418 | Lcho_1989 | Lcho_1418 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pna:Pnap_1622 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. | PFAM: amine oxidase; KEGG: azc:AZC_3405 flavin-containing protein. | 0.803 |