STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_2699KEGG: pna:Pnap_3953 succinyl-CoA synthetase, beta subunit; TIGRFAM: succinyl-CoA synthetase, beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein. (386 aa)    
Predicted Functional Partners:
Lcho_2700
TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: azo:azo3332 succinyl-CoA synthetase subunit alpha.
 0.999
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.997
Lcho_1648
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: biotin/lipoyl attachment domain-containing protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: ajs:Ajs_2096 dihydrolipoamide dehydrogenase.
  
 
 0.939
Lcho_2884
2-oxoglutarate dehydrogenase, E1 subunit; KEGG: mpt:Mpe_A2013 alpha-ketoglutarate decarboxylase; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region.
 
 
 0.898
Lcho_3027
KEGG: mpt:Mpe_A0771 hypothetical protein.
  
 0.896
Lcho_1462
PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: rfr:Rfer_3858 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit.
  
 
 0.875
Lcho_2701
KEGG: mpt:Mpe_A2165 type II citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.868
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.850
Lcho_2706
TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: mpt:Mpe_A2170 putative succinate dehydrogenase cytochrome b-556 subunit.
  
  
 0.822
Lcho_2769
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: mpt:Mpe_A2468 isocitrate dehydrogenase.
  
  
 0.815
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.