STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_2820KEGG: mpt:Mpe_A1264 hypothetical protein. (151 aa)    
Predicted Functional Partners:
greA
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
       0.795
Lcho_0604
PFAM: Anti sigma-E protein RseA family protein; KEGG: mpt:Mpe_A0643 putative transmembrane sigma-E factor negative regulatory transcription regulator protein.
  
     0.737
Lcho_0489
PFAM: O-antigen polymerase; KEGG: mpt:Mpe_A0063 O-antigen polymerase.
  
     0.733
Lcho_0265
KEGG: mpt:Mpe_A0595 hypothetical protein.
  
     0.684
Lcho_3265
KEGG: pna:Pnap_0301 hypothetical protein.
  
     0.679
Lcho_3914
KEGG: mpt:Mpe_A0205 hypothetical protein.
  
     0.674
Lcho_0291
KEGG: cau:Caur_3354 hypothetical protein.
  
     0.670
Lcho_0679
KEGG: mpt:Mpe_A1102 hypothetical protein.
  
     0.670
Lcho_0298
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: mpt:Mpe_A0605 hypothetical protein.
  
     0.658
Lcho_2742
PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: mpt:Mpe_A3165 putative HNS-like transcription regulator protein.
  
     0.651
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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