STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_2899PFAM: nitrogen regulatory protein P-II; KEGG: mpt:Mpe_A2112 putative nitrogen regulatory p-II transcription regulator protein; Belongs to the P(II) protein family. (112 aa)    
Predicted Functional Partners:
Lcho_0663
TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: abo:ABO_1476 ammonium transporter, putative.
 
 0.978
glnD
UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
 
 0.972
Lcho_2647
PFAM: Rh family protein/ammonium transporter; KEGG: pol:Bpro_4891 Rh-like protein/ammonium transporter.
 
 0.968
Lcho_3583
Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: mpt:Mpe_A2074 putative nitrogen regulation protein NR(II).
  
 0.968
Lcho_0157
TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: mfa:Mfla_0434 ammonium transporter.
 
 0.913
Lcho_3941
TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: pol:Bpro_0184 ammonium transporter.
 
 0.904
Lcho_4373
TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: cvi:CV_4003 ammonium transporter.
 
 0.821
argA
TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: mpt:Mpe_A1373 N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily.
   
 
 0.670
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 
 0.650
Lcho_4212
KEGG: mfa:Mfla_1283 PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
 
 0.580
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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