STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Lcho_3069TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: dar:Daro_2440 UDP-glucose/GDP-mannose dehydrogenase:6-phosphogluconate dehydrogenase, NAD-binding; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (426 aa)    
Predicted Functional Partners:
Lcho_3068
PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: tbd:Tbd_0099 NAD-dependent epimerase/dehydratase.
 
 
 0.991
Lcho_1385
PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: ade:Adeh_4176 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
 
 0.974
Lcho_0642
PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: esa:ESA_03772 hypothetical protein.
 
 
 0.966
Lcho_0289
PFAM: oxidoreductase domain protein; Oxidoreductase domain; homoserine dehydrogenase NAD-binding; KEGG: bbr:BB0155 probable oxidoreductase.
 
 
 0.929
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
  
 
 0.918
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
    
  0.904
lpxA
acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
    
 0.823
Lcho_0618
PFAM: glycosyl transferase family 4; KEGG: mpt:Mpe_A0630 putative undecaprenyl phosphate N-acetylglucosaminyltransferase.
 
  
 0.686
Lcho_3505
TIGRFAM: secretion ATPase, PEP-CTERM locus subfamily; SMART: AAA ATPase; KEGG: eba:ebA4256 general secretion pathway protein-related protein; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
  
  
 0.640
Lcho_2319
Undecaprenyl-phosphate glucose phosphotransferase; KEGG: mpt:Mpe_A1065 polysaccharide biosynthesis protein, putative; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: sugar transferase.
  
  
 0.547
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.