STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_3147TIGRFAM: formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme (Fae); KEGG: mpt:Mpe_A2612 formaldehyde-activating enzyme. (169 aa)    
Predicted Functional Partners:
Lcho_3152
Methylenetetrahydrofolate dehydrogenase (NADP(+)); PFAM: Methylene-tetrahydromethanopterin dehydrogenase; KEGG: mpt:Mpe_A2607 methylene tetrahydromethanopterin dehydrogenase/methylenetetrahydrofolate dehydrogenase, putative.
 
  
 0.990
ffsA
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.
 
  
 0.979
Lcho_3106
TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: Pyrrolo-quinoline quinone; KEGG: mpt:Mpe_A3393 putative methanol dehydrogenase protein, large subunit.
  
  
 0.932
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
 
   
 0.925
Lcho_3132
TIGRFAM: formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme (Fae); KEGG: mpt:Mpe_A2627 putative formaldehyde-activating enzyme.
  
  
 
0.924
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.918
Lcho_3151
PFAM: protein of unknown function DUF201; KEGG: mpt:Mpe_A2608 hypothetical protein.
 
   
 0.896
Lcho_3153
TIGRFAM: beta-ribofuranosylaminobenzene 5'-phosphate synthase family; PFAM: GHMP kinase; KEGG: mpt:Mpe_A2606 kinase, GHMP family, putative.
 
   
 0.896
Lcho_3149
TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: mpt:Mpe_A2610 ribosomal protein S6 modification protein, putative; Belongs to the RimK family.
 
     0.890
Lcho_3148
PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mpt:Mpe_A2611 ATP:dephospho-CoA triphosphoribosyl transferase.
 
     0.885
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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