Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_3207PFAM: major facilitator superfamily MFS_1; KEGG: rfr:Rfer_0434 major facilitator superfamily MFS_1. (401 aa)    
Predicted Functional Partners:
Lcho_3206
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: bha:BH2165 hypothetical protein.
  
    0.603
Lcho_3205
PFAM: protein of unknown function DUF1037; KEGG: smd:Smed_3808 protein of unknown function DUF1037.
       0.586
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.513
Lcho_3857
PFAM: YaeQ family protein; KEGG: mfa:Mfla_0160 YaeQ.
   
    0.501
Lcho_4328
PFAM: AP endonuclease 2 domain protein; Xylose isomerase domain protein TIM barrel; KEGG: bra:BRADO0446 conserved hypothetical protein; putative xylose isomerase-like.
 
   
 0.440
Lcho_1658
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.439
Lcho_2810
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.439
Lcho_3204
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: gur:Gura_0276 helix-turn-helix-domain containing protein, AraC type.
     
 0.413
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
Server load: low (18%) [HD]