STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_3267PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: mpt:Mpe_A0165 putative ATPase protein. (795 aa)    
Predicted Functional Partners:
Lcho_3268
PFAM: homocysteine S-methyltransferase; KEGG: mpt:Mpe_A0166 5-methyltetrahydrofolate--homocysteine S-methyltransferase.
   
  0.731
Lcho_0346
KEGG: mpt:Mpe_A0279 hypothetical protein.
  
     0.630
Lcho_3262
KEGG: mpt:Mpe_A3635 hypothetical protein.
 
     0.616
Lcho_3424
PFAM: General secretion pathway L; KEGG: mpt:Mpe_A3133 general secretion pathway protein L.
  
     0.609
Lcho_3720
KEGG: pna:Pnap_3103 hypothetical protein.
  
     0.584
Lcho_3266
KEGG: mpt:Mpe_A3630 hypothetical protein.
 
     0.582
Lcho_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.569
Lcho_1991
PFAM: histone deacetylase superfamily; KEGG: mpt:Mpe_A1507 hypothetical protein.
 
 
 0.562
Lcho_0796
PFAM: aromatic-ring-hydroxylating dioxygenase beta subunit; KEGG: aav:Aave_0166 aromatic-ring-hydroxylating dioxygenase, beta subunit.
  
     0.551
Lcho_3422
KEGG: mpt:Mpe_A3131 general secretion pathway protein J.
  
     0.538
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.