STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_3279PFAM: acylphosphatase; KEGG: dar:Daro_1185 acylphosphatase. (92 aa)    
Predicted Functional Partners:
Lcho_2797
PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase; KEGG: rfr:Rfer_2974 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
    
 0.924
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.912
ackA-2
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.912
Lcho_0565
PFAM: Aldehyde Dehydrogenase_; KEGG: rsh:Rsph17029_2952 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.905
Lcho_0928
PFAM: Aldehyde Dehydrogenase_; KEGG: sil:SPO0097 aldehyde dehydrogenase family protein.
    
 0.905
Lcho_2104
PFAM: Aldehyde Dehydrogenase_; KEGG: pna:Pnap_3013 aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family.
    
 0.905
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.901
Lcho_3655
TIGRFAM: benzoate-CoA ligase family; PFAM: AMP-dependent synthetase and ligase; KEGG: rfr:Rfer_0216 benzoate-CoA ligase family.
     
 0.901
Lcho_1212
Coenzyme A transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.
     
  0.900
Lcho_3635
PFAM: amidohydrolase 2; KEGG: pna:Pnap_2029 amidohydrolase 2.
     
  0.800
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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