STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_3341Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (305 aa)    
Predicted Functional Partners:
Lcho_3340
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 0.998
Lcho_3342
KEGG: mpt:Mpe_A2272 4-oxalocrotonate decarboxylase; TIGRFAM: 4-oxalocrotonate decarboxylase; PFAM: Hydratase/decarboxylase.
 
  
 0.979
Lcho_1366
TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: pna:Pnap_2310 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 0.976
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.976
leuA-2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.976
Lcho_3343
2-oxopent-4-enoate hydratase; KEGG: reu:Reut_B5691 4-oxalocrotonate decarboxylase; TIGRFAM: 2-oxopent-4-enoate hydratase; PFAM: Hydratase/decarboxylase.
 
  
 0.962
Lcho_0565
PFAM: Aldehyde Dehydrogenase_; KEGG: rsh:Rsph17029_2952 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.907
Lcho_0928
PFAM: Aldehyde Dehydrogenase_; KEGG: sil:SPO0097 aldehyde dehydrogenase family protein.
    
 0.907
Lcho_2104
PFAM: Aldehyde Dehydrogenase_; KEGG: pna:Pnap_3013 aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family.
    
 0.907
Lcho_2797
PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase; KEGG: rfr:Rfer_2974 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
     
 0.906
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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