STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_33432-oxopent-4-enoate hydratase; KEGG: reu:Reut_B5691 4-oxalocrotonate decarboxylase; TIGRFAM: 2-oxopent-4-enoate hydratase; PFAM: Hydratase/decarboxylase. (260 aa)    
Predicted Functional Partners:
Lcho_3344
PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: vei:Veis_2786 alpha/beta hydrolase fold.
 
 
 0.992
Lcho_3340
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.990
Lcho_3341
Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.962
Lcho_3342
KEGG: mpt:Mpe_A2272 4-oxalocrotonate decarboxylase; TIGRFAM: 4-oxalocrotonate decarboxylase; PFAM: Hydratase/decarboxylase.
 
  
 
0.958
Lcho_1122
PFAM: HpcH/HpaI aldolase; KEGG: mpt:Mpe_A0974 2-dehydro-3-deoxyglucarate aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 0.765
Lcho_3356
TIGRFAM: catechol 2,3 dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: vei:Veis_2789 catechol 2,3-dioxygenase.
 
  
 0.760
Lcho_3339
TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: 4-oxalocrotonate tautomerase; KEGG: ajs:Ajs_0227 4-oxalocrotonate tautomerase family enzyme.
 
   
 0.680
Lcho_3361
PFAM: monooxygenase component MmoB/DmpM; KEGG: vei:Veis_2794 monooxygenase component MmoB/DmpM.
 
     0.486
Lcho_3357
PFAM: ferredoxin; KEGG: vei:Veis_2790 ferredoxin.
 
     0.483
Lcho_3360
PFAM: methane/phenol/toluene hydroxylase; YHS domain protein; KEGG: vei:Veis_2793 methane/phenol/toluene hydroxylase.
 
     0.480
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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