node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Lcho_3489 | Lcho_3490 | Lcho_3489 | Lcho_3490 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Conserved hypothetical protein; Displays ATPase and GTPase activities. | 0.793 |
Lcho_3489 | Lcho_3491 | Lcho_3489 | Lcho_3491 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | PFAM: peptidase S16 lon domain protein; KEGG: mpt:Mpe_A3337 hypothetical protein. | 0.725 |
Lcho_3489 | hrcA | Lcho_3489 | Lcho_3487 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.738 |
Lcho_3489 | lexA | Lcho_3489 | Lcho_2082 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Transcriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.744 |
Lcho_3489 | nadK | Lcho_3489 | Lcho_3488 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.847 |
Lcho_3489 | pheT | Lcho_3489 | Lcho_1750 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | phenylalanyl-tRNA synthetase, beta subunit; KEGG: mpt:Mpe_A1883 phenylalanine--tRNA ligase; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. | 0.731 |
Lcho_3489 | recA | Lcho_3489 | Lcho_0497 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.786 |
Lcho_3489 | ruvA | Lcho_3489 | Lcho_3953 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.697 |
Lcho_3489 | ruvB | Lcho_3489 | Lcho_3954 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.669 |
Lcho_3489 | xseA | Lcho_3489 | Lcho_2552 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.701 |
Lcho_3490 | Lcho_3489 | Lcho_3490 | Lcho_3489 | Conserved hypothetical protein; Displays ATPase and GTPase activities. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.793 |
Lcho_3490 | Lcho_3491 | Lcho_3490 | Lcho_3491 | Conserved hypothetical protein; Displays ATPase and GTPase activities. | PFAM: peptidase S16 lon domain protein; KEGG: mpt:Mpe_A3337 hypothetical protein. | 0.805 |
Lcho_3490 | hrcA | Lcho_3490 | Lcho_3487 | Conserved hypothetical protein; Displays ATPase and GTPase activities. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.635 |
Lcho_3490 | nadK | Lcho_3490 | Lcho_3488 | Conserved hypothetical protein; Displays ATPase and GTPase activities. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.708 |
Lcho_3491 | Lcho_3489 | Lcho_3491 | Lcho_3489 | PFAM: peptidase S16 lon domain protein; KEGG: mpt:Mpe_A3337 hypothetical protein. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.725 |
Lcho_3491 | Lcho_3490 | Lcho_3491 | Lcho_3490 | PFAM: peptidase S16 lon domain protein; KEGG: mpt:Mpe_A3337 hypothetical protein. | Conserved hypothetical protein; Displays ATPase and GTPase activities. | 0.805 |
Lcho_3491 | hrcA | Lcho_3491 | Lcho_3487 | PFAM: peptidase S16 lon domain protein; KEGG: mpt:Mpe_A3337 hypothetical protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.494 |
Lcho_3491 | nadK | Lcho_3491 | Lcho_3488 | PFAM: peptidase S16 lon domain protein; KEGG: mpt:Mpe_A3337 hypothetical protein. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.696 |
hrcA | Lcho_3489 | Lcho_3487 | Lcho_3489 | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.738 |
hrcA | Lcho_3490 | Lcho_3487 | Lcho_3490 | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Conserved hypothetical protein; Displays ATPase and GTPase activities. | 0.635 |