STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fur-2Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: dac:Daci_4458 ferric uptake regulator, Fur family; Belongs to the Fur family. (137 aa)    
Predicted Functional Partners:
Lcho_3562
ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bpe:BP3082 putative transport protein ATP-binding.
  
  
 0.772
Lcho_3561
PFAM: ABC-3 protein; KEGG: cvi:CV_3065 high-affinity zinc transport system permease protein.
  
  
 0.682
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.647
Lcho_3560
PFAM: periplasmic solute binding protein; KEGG: mex:Mext_2875 periplasmic solute binding protein; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.627
Lcho_0258
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
  
 0.598
Lcho_2805
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: mpt:Mpe_A1283 thioredoxin 1; Belongs to the thioredoxin family.
  
 
 0.576
Lcho_4107
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: tbd:Tbd_2401 thioredoxin.
  
 
 0.576
Lcho_3396
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: mpt:Mpe_A3103 glutamate synthase (ferredoxin).
     
 0.534
rpoH
RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
  
 
 0.532
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.527
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.