STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_3727PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mpt:Mpe_A1171 formate dehydrogenase iron-sulfur subunit. (214 aa)    
Predicted Functional Partners:
Lcho_3725
TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: mpt:Mpe_A1173 formate dehydrogenase subunit C precursor.
 
 0.999
Lcho_3728
PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: mpt:Mpe_A1170 formate dehydrogenase large subunit precursor; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 0.997
Lcho_2750
TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: mpt:Mpe_A3710 NAD-dependent formate dehydrogenase alpha subunit.
  
 
 0.960
fdhD-2
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
   
 0.919
Lcho_2752
PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: mpt:Mpe_A3708 NAD-dependent formate dehydrogenase gamma subunit.
    
 0.907
Lcho_2751
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: mpt:Mpe_A3709 NADH dehydrogenase (quinone).
    
 0.906
Lcho_0159
PFAM: N-formylglutamate amidohydrolase; KEGG: azo:azo3002 conserved hypothetical formylglutamte amindohyrolase.
    
  0.901
Lcho_2749
Hypothetical protein; KEGG: mca:MCA1389 formate dehydrogenase, delta subunit.
     
  0.900
Lcho_2976
KEGG: pol:Bpro_1716 hypothetical protein.
     
  0.900
Lcho_3256
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
     
  0.900
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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