STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_3940TIGRFAM: glutamate--cysteine ligase; PFAM: glutamate--cysteine ligase GshA; KEGG: mpt:Mpe_A0173 putative glutamate--cysteine ligase. (431 aa)    
Predicted Functional Partners:
secF
Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
 
 0.948
gshB
KEGG: rfr:Rfer_0765 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family.
 
  
 0.939
Lcho_3225
Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
  
  
  0.918
Lcho_1764
TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: mpt:Mpe_A2774 alanyl aminopeptidase.
   
 
 0.913
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
    
 0.908
Lcho_2123
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinase B/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: mpt:Mpe_A2968 5-oxoprolinase (ATP-hydrolyzing).
    
  0.903
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 
  0.901
gshA
TIGRFAM: glutamate--cysteine ligase; KEGG: pol:Bpro_3399 glutamate--cysteine ligase, monofunctional; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
  0.900
Lcho_2560
Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: ajs:Ajs_1042 gamma-glutamyltransferase.
     
 0.900
Lcho_4355
Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: tth:TTC0403 gamma-glutamyltranspeptidase.
     
 0.900
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.