STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_3966TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: rfr:Rfer_1673 diguanylate cyclase. (345 aa)    
Predicted Functional Partners:
Lcho_4175
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: eba:ebA6472 putative response regulator receiver; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 0.895
Lcho_3195
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: xom:XOO_3074 phosphodiesterase.
 
 0.819
Lcho_0342
Diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: aav:Aave_0649 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s).
 
 0.815
Lcho_2671
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: mpt:Mpe_A2313 GGDEF domain containing protein.
  
     0.765
Lcho_2004
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mpt:Mpe_A2326 GGDEF domain containing protein.
  
     0.758
Lcho_3967
CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; KEGG: aav:Aave_0905 CheA signal transduction histidine kinase.
  
  
 0.719
Lcho_3702
KEGG: rfr:Rfer_2262 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAC repeat-containing protein.
 
0.686
Lcho_4069
PAS/PAC sensor hybrid histidine kinase; KEGG: azo:azo2482 putative hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.636
Lcho_3968
PFAM: chemotaxis sensory transducer; KEGG: mpt:Mpe_A3187 twitching motility protein.
   
   0.625
Lcho_2095
Diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase HAMP region domain protein; KEGG: mpt:Mpe_A1878 hypothetical protein.
 
  
 0.618
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.