STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_4115PFAM: Two component regulator propeller; KEGG: mxa:MXAN_7206 sensor histidine kinase/response regulator. (357 aa)    
Predicted Functional Partners:
Lcho_4116
PFAM: cytochrome c class I; KEGG: syx:SynWH7803_0752 cytochrome c6.
 
     0.866
Lcho_4113
KEGG: ava:Ava_1029 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
 0.744
Lcho_4114
Two component regulator propeller domain protein; KEGG: sus:Acid_2684 histidine kinase.
 
    
0.729
Lcho_4122
KEGG: nca:Noca_2201 ResB family protein.
  
     0.721
Lcho_4123
KEGG: rfr:Rfer_0259 hypothetical protein.
  
     0.665
Lcho_4118
Putative sensor with HAMP domain; PFAM: histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: rfr:Rfer_0246 histidine kinase.
 
 
   0.663
Lcho_4137
PFAM: cytochrome c class I; KEGG: rme:Rmet_6106 putative high-affinity Fe2+/Pb2+ permease.
  
     0.662
Lcho_4131
KEGG: gur:Gura_2745 hypothetical protein.
  
     0.650
Lcho_4134
KEGG: gsu:GSU0618 cytochrome c family protein.
  
     0.625
Lcho_4117
Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: rfr:Rfer_0247 two component, sigma54 specific, transcriptional regulator, fis family.
   
   0.618
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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