STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcho_4202PFAM: thioesterase superfamily protein; KEGG: dac:Daci_5992 thioesterase superfamily protein. (154 aa)    
Predicted Functional Partners:
Lcho_3434
PFAM: AMP-dependent synthetase and ligase; KEGG: pna:Pnap_3607 AMP-dependent synthetase and ligase.
 
   
 0.701
Lcho_3438
KEGG: pna:Pnap_3611 hypothetical protein.
  
     0.666
Lcho_3441
KEGG: ajs:Ajs_0464 putative phenylacetate-CoA ligase.
 
  
 0.660
Lcho_3437
PFAM: inner-membrane translocator; KEGG: aav:Aave_0784 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
     0.599
Lcho_4201
Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: reh:H16_A0165 transcriptional regulator, MerR-family.
  
  
 0.583
Lcho_4203
Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
       0.571
aceK
(Isocitrate dehydrogenase (NADP(+))) kinase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
       0.551
Lcho_3439
ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_0599 ABC transporter related.
 
     0.529
Lcho_3436
PFAM: inner-membrane translocator; KEGG: pol:Bpro_0602 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
     0.518
Lcho_3435
ABC transporter-related protein; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ajs:Ajs_0469 ABC transporter related.
 
     0.510
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.