STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dctASodium:dicarboxylate symporter; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (447 aa)    
Predicted Functional Partners:
Lcho_4339
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: bja:blr3730 two-component hybrid sensor and regulator.
 
   
 0.679
Lcho_4338
Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: bra:BRADO2304 C4-dicarboxylate transport transcriptional regulatory protein (response regulator in two-component reguatory system).
 
   
 0.655
Lcho_2705
TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: mpt:Mpe_A2169 transmembrane succinate dehydrogenase (hydrophobic membrane anchor subunit) oxidoreductase protein.
   
  
 0.629
Lcho_0236
Histidine kinase; PFAM: Na+/solute symporter; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rfr:Rfer_3779 periplasmic sensor signal transduction histidine kinase.
  
  
 0.616
Lcho_0359
PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: aav:Aave_1095 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), phosphate acetyltransferase.
  
  
 0.557
Lcho_3916
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: ajs:Ajs_4106 malic enzyme; Belongs to the malic enzymes family.
  
  
 0.557
Lcho_2701
KEGG: mpt:Mpe_A2165 type II citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
  
 0.514
Lcho_1464
Multi-sensor hybrid histidine kinase; KEGG: aha:AHA_2188 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein.
     
 0.501
Lcho_4069
PAS/PAC sensor hybrid histidine kinase; KEGG: azo:azo2482 putative hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
     
 0.491
Lcho_0149
PFAM: Ankyrin; KEGG: pol:Bpro_4103 ankyrin.
 
 0.482
Your Current Organism:
Leptothrix cholodnii
NCBI taxonomy Id: 395495
Other names: L. cholodnii SP-6, Leptothrix cholodnii SP-6, Leptothrix cholodnii str. SP-6, Leptothrix cholodnii strain SP-6
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