node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEC21722.1 | SEC63813.1 | SAMN05216205_1777 | SAMN05216205_2848 | ATP-dependent DNA helicase RecQ. | ATP-dependent DNA helicase, RecQ-like. | 0.738 |
SEC21722.1 | SEC73796.1 | SAMN05216205_1777 | SAMN05216205_3128 | ATP-dependent DNA helicase RecQ. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.906 |
SEC21722.1 | SEC75777.1 | SAMN05216205_1777 | SAMN05216205_3184 | ATP-dependent DNA helicase RecQ. | ATP-dependent DNA helicase UvrD. | 0.910 |
SEC21722.1 | mutL | SAMN05216205_1777 | SAMN05216205_2583 | ATP-dependent DNA helicase RecQ. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.921 |
SEC21722.1 | polA | SAMN05216205_1777 | SAMN05216205_3028 | ATP-dependent DNA helicase RecQ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.993 |
SEC21722.1 | recA | SAMN05216205_1777 | SAMN05216205_4505 | ATP-dependent DNA helicase RecQ. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.983 |
SEC21722.1 | rpoB | SAMN05216205_1777 | SAMN05216205_3709 | ATP-dependent DNA helicase RecQ. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.420 |
SEC21722.1 | topA | SAMN05216205_1777 | SAMN05216205_1391 | ATP-dependent DNA helicase RecQ. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.993 |
SEC63813.1 | SEC21722.1 | SAMN05216205_2848 | SAMN05216205_1777 | ATP-dependent DNA helicase, RecQ-like. | ATP-dependent DNA helicase RecQ. | 0.738 |
SEC63813.1 | SEC73796.1 | SAMN05216205_2848 | SAMN05216205_3128 | ATP-dependent DNA helicase, RecQ-like. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.906 |
SEC63813.1 | SEC75777.1 | SAMN05216205_2848 | SAMN05216205_3184 | ATP-dependent DNA helicase, RecQ-like. | ATP-dependent DNA helicase UvrD. | 0.915 |
SEC63813.1 | mutL | SAMN05216205_2848 | SAMN05216205_2583 | ATP-dependent DNA helicase, RecQ-like. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.921 |
SEC63813.1 | polA | SAMN05216205_2848 | SAMN05216205_3028 | ATP-dependent DNA helicase, RecQ-like. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.993 |
SEC63813.1 | recA | SAMN05216205_2848 | SAMN05216205_4505 | ATP-dependent DNA helicase, RecQ-like. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.983 |
SEC63813.1 | rpoB | SAMN05216205_2848 | SAMN05216205_3709 | ATP-dependent DNA helicase, RecQ-like. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.420 |
SEC63813.1 | topA | SAMN05216205_2848 | SAMN05216205_1391 | ATP-dependent DNA helicase, RecQ-like. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.993 |
SEC73796.1 | SEC21722.1 | SAMN05216205_3128 | SAMN05216205_1777 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase RecQ. | 0.906 |
SEC73796.1 | SEC63813.1 | SAMN05216205_3128 | SAMN05216205_2848 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase, RecQ-like. | 0.906 |
SEC73796.1 | SEC75777.1 | SAMN05216205_3128 | SAMN05216205_3184 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase UvrD. | 0.945 |
SEC73796.1 | mutL | SAMN05216205_3128 | SAMN05216205_2583 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.971 |