STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sasAHistidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs. (387 aa)    
Predicted Functional Partners:
ACL46061.1
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: amr:AM1_4053 two-component transcriptional regulator.
 
  0.987
ACL43448.1
PFAM: response regulator receiver; KEGG: tel:tll0571 two-component response regulator.
 
   0.940
kaiC
Putative circadian clock protein, KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family.
  
 
 
 0.934
ACL43135.1
PFAM: response regulator receiver; KEGG: sus:Acid_4296 response regulator receiver protein.
 
   0.914
ACL47508.1
PFAM: regulatory protein LuxR; response regulator receiver; KEGG: amr:AM1_1808 two component LuxR family transcriptional regulator.
 
 
   0.895
ACL45449.1
KEGG: npu:Npun_F0263 MCP methyltransferase, CheR-type with PAS/PAC sensor; TIGRFAM: PAS sensor protein; PFAM: MCP methyltransferase CheR-type; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
      0.875
ACL43764.1
PFAM: response regulator receiver; ATP-binding region ATPase domain protein; KEGG: ana:alr3121 two-component hybrid sensor and regulator.
 
   0.870
ACL46720.1
PFAM: response regulator receiver; KEGG: ava:Ava_1562 response regulator receiver signal transduction histidine kinase.
 
 0.866
ACL43500.1
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ava:Ava_1878 two component transcriptional regulator.
 
   0.843
ACL46934.1
PFAM: regulatory protein LuxR; response regulator receiver; KEGG: amr:AM1_2217 two component LuxR family transcriptional regulator.
 
 
   0.839
Your Current Organism:
Cyanothece sp. PCC7425
NCBI taxonomy Id: 395961
Other names: C. sp. PCC 7425, Cyanothece sp. ATCC 29141, Cyanothece sp. PCC 7425, Synechococcus sp. PCC 7425
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