STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpFPFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: cyt:cce_0998 N-(5'-phosphoribosyl) anthranilate isomerase; Belongs to the TrpF family. (219 aa)    
Predicted Functional Partners:
trpC
PFAM: Indole-3-glycerol phosphate synthase; KEGG: amr:AM1_4360 indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
 0.999
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.998
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 0.997
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 0.997
ACL46802.1
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: amr:AM1_1430 anthranilate synthase component II.
  
 0.986
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
  
 0.951
ACL43968.1
PFAM: Glycosyl transferase, family 3-like; KEGG: npu:Npun_F1535 glycosyl transferase family protein.
 
  
 0.950
ACL43609.1
KEGG: amr:AM1_5363 anthranilate synthase component I-like protein; TIGRFAM: para-aminobenzoate synthase component I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like.
 
  
 0.938
ACL43126.1
PFAM: Aldose 1-epimerase; KEGG: ava:Ava_4277 aldose 1-epimerase.
     
 0.775
ACL47413.1
TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: amr:AM1_1109 isochorismate synthase.
  
   
 0.701
Your Current Organism:
Cyanothece sp. PCC7425
NCBI taxonomy Id: 395961
Other names: C. sp. PCC 7425, Cyanothece sp. ATCC 29141, Cyanothece sp. PCC 7425, Synechococcus sp. PCC 7425
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