STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bind_0041PFAM: Aldehyde Dehydrogenase_; KEGG: cak:Caul_4341 aldehyde dehydrogenase_; Belongs to the aldehyde dehydrogenase family. (469 aa)    
Predicted Functional Partners:
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.929
Bind_0618
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: azc:AZC_0575 methylmalonate-semialdehyde dehydrogenase.
  
  
 
0.920
Bind_0175
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: xau:Xaut_3248 methylmalonate-semialdehyde dehydrogenase.
  
  
 
0.919
Bind_2495
TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: gvi:glr4425 glutathione dependent formaldehyde dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.917
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.915
Bind_2852
PFAM: Aldehyde Dehydrogenase_; KEGG: gbe:GbCGDNIH1_1022 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.914
Bind_0615
KEGG: rle:pRL110406 putative 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; Belongs to the HIBADH-related family.
  
 
 0.911
Bind_1788
3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: rpb:RPB_3394 3-hydroxyisobutyrate dehydrogenase.
  
 
 0.909
Bind_1794
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: dps:DP2330 similar to indole-3-pyruvate decarboxylase.
   
 0.907
Bind_3389
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: gdi:GDI0172 pyruvate decarboxylase.
   
 0.907
Your Current Organism:
Beijerinckia indica
NCBI taxonomy Id: 395963
Other names: B. indica subsp. indica ATCC 9039, Beijerinckia indica subsp. indica ATCC 9039, Beijerinckia indica subsp. indica str. ATCC 9039, Beijerinckia indica subsp. indica strain ATCC 9039
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