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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bind_0618TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: azc:AZC_0575 methylmalonate-semialdehyde dehydrogenase. (499 aa)    
Predicted Functional Partners:
Bind_0615
KEGG: rle:pRL110406 putative 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; Belongs to the HIBADH-related family.
 
 
 0.968
Bind_0613
PFAM: AMP-dependent synthetase and ligase; KEGG: dol:Dole_1499 AMP-dependent synthetase and ligase.
  
 0.935
Bind_1242
PFAM: aminotransferase class-III; KEGG: rpe:RPE_0915 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.925
Bind_1756
KEGG: rru:Rru_A1310 acetyl-CoA C-acyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.924
Bind_1788
3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: rpb:RPB_3394 3-hydroxyisobutyrate dehydrogenase.
 
 
 0.921
Bind_0041
PFAM: Aldehyde Dehydrogenase_; KEGG: cak:Caul_4341 aldehyde dehydrogenase_; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.920
Bind_1317
PFAM: carboxyl transferase; KEGG: ret:RHE_CH02232 propionyl-CoA carboxylase beta chain protein.
   
 
 0.919
Bind_2202
PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase; KEGG: azc:AZC_2420 phosphate acetyl/butyryltransferase family protein.
  
 
 0.913
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.911
Bind_0950
TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: afw:Anae109_2819 quinone oxidoreductase putative YhdH/YhfP.
    
  0.908
Your Current Organism:
Beijerinckia indica
NCBI taxonomy Id: 395963
Other names: B. indica subsp. indica ATCC 9039, Beijerinckia indica subsp. indica ATCC 9039, Beijerinckia indica subsp. indica str. ATCC 9039, Beijerinckia indica subsp. indica strain ATCC 9039
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