| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_0267 | Bind_0712 | Bind_0267 | Bind_0712 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | 0.563 |
| Bind_0267 | ccmC | Bind_0267 | Bind_0711 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.548 |
| Bind_0709 | Bind_0710 | Bind_0709 | Bind_0710 | TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: rpa:RPA0206 putative cytochrome c biogenesis protein, thiol:disulfide interchange protein. | Hypothetical protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. | 0.783 |
| Bind_0709 | Bind_0712 | Bind_0709 | Bind_0712 | TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: rpa:RPA0206 putative cytochrome c biogenesis protein, thiol:disulfide interchange protein. | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | 0.440 |
| Bind_0709 | ccmC | Bind_0709 | Bind_0711 | TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: rpa:RPA0206 putative cytochrome c biogenesis protein, thiol:disulfide interchange protein. | Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.978 |
| Bind_0710 | Bind_0709 | Bind_0710 | Bind_0709 | Hypothetical protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. | TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: rpa:RPA0206 putative cytochrome c biogenesis protein, thiol:disulfide interchange protein. | 0.783 |
| Bind_0710 | Bind_0712 | Bind_0710 | Bind_0712 | Hypothetical protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | 0.439 |
| Bind_0710 | ccmC | Bind_0710 | Bind_0711 | Hypothetical protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. | Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.783 |
| Bind_0712 | Bind_0267 | Bind_0712 | Bind_0267 | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.563 |
| Bind_0712 | Bind_0709 | Bind_0712 | Bind_0709 | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: rpa:RPA0206 putative cytochrome c biogenesis protein, thiol:disulfide interchange protein. | 0.440 |
| Bind_0712 | Bind_0710 | Bind_0712 | Bind_0710 | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | Hypothetical protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. | 0.439 |
| Bind_0712 | Bind_0713 | Bind_0712 | Bind_0713 | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | KEGG: mlo:mlr7790 dihydroorotase; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase. | 0.534 |
| Bind_0712 | Bind_1136 | Bind_0712 | Bind_1136 | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: xau:Xaut_3105 methyltransferase type 11. | 0.558 |
| Bind_0712 | Bind_1308 | Bind_0712 | Bind_1308 | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | NADH dehydrogenase (ubiquinone); PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: bbt:BBta_0224 hypothetical protein. | 0.446 |
| Bind_0712 | Bind_1550 | Bind_0712 | Bind_1550 | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | PFAM: ETC complex I subunit conserved region; KEGG: mex:Mext_3134 ETC complex I subunit conserved region. | 0.565 |
| Bind_0712 | Bind_2392 | Bind_0712 | Bind_2392 | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. | 0.422 |
| Bind_0712 | Bind_3117 | Bind_0712 | Bind_3117 | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: atc:AGR_C_3401 conserved hypothetical protein NMB0773; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.420 |
| Bind_0712 | ccmC | Bind_0712 | Bind_0711 | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. | 0.439 |
| Bind_0713 | Bind_0712 | Bind_0713 | Bind_0712 | KEGG: mlo:mlr7790 dihydroorotase; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase. | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | 0.534 |
| Bind_1136 | Bind_0712 | Bind_1136 | Bind_0712 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: xau:Xaut_3105 methyltransferase type 11. | TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: rpa:RPA1068 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family. | 0.558 |