| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_0119 | Bind_0427 | Bind_0119 | Bind_0427 | PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: gdi:GDI1720 putative pyruvate dehydrogenase E2 component. | KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.926 |
| Bind_0119 | Bind_0767 | Bind_0119 | Bind_0767 | PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: gdi:GDI1720 putative pyruvate dehydrogenase E2 component. | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | 0.924 |
| Bind_0119 | Bind_2199 | Bind_0119 | Bind_2199 | PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: gdi:GDI1720 putative pyruvate dehydrogenase E2 component. | KEGG: mex:Mext_4794 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | 0.820 |
| Bind_0119 | Bind_2202 | Bind_0119 | Bind_2202 | PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: gdi:GDI1720 putative pyruvate dehydrogenase E2 component. | PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase; KEGG: azc:AZC_2420 phosphate acetyl/butyryltransferase family protein. | 0.959 |
| Bind_0119 | Bind_2747 | Bind_0119 | Bind_2747 | PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: gdi:GDI1720 putative pyruvate dehydrogenase E2 component. | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: atc:AGR_C_4790 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.671 |
| Bind_0119 | Bind_3058 | Bind_0119 | Bind_3058 | PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: gdi:GDI1720 putative pyruvate dehydrogenase E2 component. | KEGG: azc:AZC_3903 thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.926 |
| Bind_0119 | acsA | Bind_0119 | Bind_0053 | PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: gdi:GDI1720 putative pyruvate dehydrogenase E2 component. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.919 |
| Bind_0119 | sucC | Bind_0119 | Bind_3605 | PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: gdi:GDI1720 putative pyruvate dehydrogenase E2 component. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.950 |
| Bind_0119 | sucD | Bind_0119 | Bind_3606 | PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: gdi:GDI1720 putative pyruvate dehydrogenase E2 component. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.928 |
| Bind_0427 | Bind_0119 | Bind_0427 | Bind_0119 | KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: gdi:GDI1720 putative pyruvate dehydrogenase E2 component. | 0.926 |
| Bind_0427 | Bind_0767 | Bind_0427 | Bind_0767 | KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | 0.917 |
| Bind_0427 | Bind_2199 | Bind_0427 | Bind_2199 | KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | KEGG: mex:Mext_4794 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | 0.495 |
| Bind_0427 | Bind_2202 | Bind_0427 | Bind_2202 | KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase; KEGG: azc:AZC_2420 phosphate acetyl/butyryltransferase family protein. | 0.949 |
| Bind_0427 | Bind_3058 | Bind_0427 | Bind_3058 | KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | KEGG: azc:AZC_3903 thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.905 |
| Bind_0427 | acsA | Bind_0427 | Bind_0053 | KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.922 |
| Bind_0427 | sucC | Bind_0427 | Bind_3605 | KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.857 |
| Bind_0427 | sucD | Bind_0427 | Bind_3606 | KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.843 |
| Bind_0767 | Bind_0119 | Bind_0767 | Bind_0119 | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: gdi:GDI1720 putative pyruvate dehydrogenase E2 component. | 0.924 |
| Bind_0767 | Bind_0427 | Bind_0767 | Bind_0427 | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.917 |
| Bind_0767 | Bind_2199 | Bind_0767 | Bind_2199 | Succinate CoA transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase. | KEGG: mex:Mext_4794 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. | 0.955 |