| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_0041 | Bind_0175 | Bind_0041 | Bind_0175 | PFAM: Aldehyde Dehydrogenase_; KEGG: cak:Caul_4341 aldehyde dehydrogenase_; Belongs to the aldehyde dehydrogenase family. | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: xau:Xaut_3248 methylmalonate-semialdehyde dehydrogenase. | 0.919 |
| Bind_0041 | Bind_0200 | Bind_0041 | Bind_0200 | PFAM: Aldehyde Dehydrogenase_; KEGG: cak:Caul_4341 aldehyde dehydrogenase_; Belongs to the aldehyde dehydrogenase family. | PFAM: phosphate acetyl/butaryl transferase; KEGG: bch:Bcen2424_4872 phosphate acetyltransferase. | 0.804 |
| Bind_0041 | Bind_0613 | Bind_0041 | Bind_0613 | PFAM: Aldehyde Dehydrogenase_; KEGG: cak:Caul_4341 aldehyde dehydrogenase_; Belongs to the aldehyde dehydrogenase family. | PFAM: AMP-dependent synthetase and ligase; KEGG: dol:Dole_1499 AMP-dependent synthetase and ligase. | 0.822 |
| Bind_0041 | Bind_0618 | Bind_0041 | Bind_0618 | PFAM: Aldehyde Dehydrogenase_; KEGG: cak:Caul_4341 aldehyde dehydrogenase_; Belongs to the aldehyde dehydrogenase family. | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: azc:AZC_0575 methylmalonate-semialdehyde dehydrogenase. | 0.920 |
| Bind_0041 | Bind_0950 | Bind_0041 | Bind_0950 | PFAM: Aldehyde Dehydrogenase_; KEGG: cak:Caul_4341 aldehyde dehydrogenase_; Belongs to the aldehyde dehydrogenase family. | TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: afw:Anae109_2819 quinone oxidoreductase putative YhdH/YhfP. | 0.817 |
| Bind_0041 | Bind_1317 | Bind_0041 | Bind_1317 | PFAM: Aldehyde Dehydrogenase_; KEGG: cak:Caul_4341 aldehyde dehydrogenase_; Belongs to the aldehyde dehydrogenase family. | PFAM: carboxyl transferase; KEGG: ret:RHE_CH02232 propionyl-CoA carboxylase beta chain protein. | 0.838 |
| Bind_0041 | Bind_1318 | Bind_0041 | Bind_1318 | PFAM: Aldehyde Dehydrogenase_; KEGG: cak:Caul_4341 aldehyde dehydrogenase_; Belongs to the aldehyde dehydrogenase family. | PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: azc:AZC_1774 propionyl-coenzyme A carboxylase alpha polypeptide. | 0.808 |
| Bind_0041 | Bind_2202 | Bind_0041 | Bind_2202 | PFAM: Aldehyde Dehydrogenase_; KEGG: cak:Caul_4341 aldehyde dehydrogenase_; Belongs to the aldehyde dehydrogenase family. | PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase; KEGG: azc:AZC_2420 phosphate acetyl/butyryltransferase family protein. | 0.826 |
| Bind_0041 | Bind_2453 | Bind_0041 | Bind_2453 | PFAM: Aldehyde Dehydrogenase_; KEGG: cak:Caul_4341 aldehyde dehydrogenase_; Belongs to the aldehyde dehydrogenase family. | PFAM: phosphate acetyl/butaryl transferase; KEGG: bch:Bcen2424_4872 phosphate acetyltransferase. | 0.804 |
| Bind_0041 | acsA | Bind_0041 | Bind_0053 | PFAM: Aldehyde Dehydrogenase_; KEGG: cak:Caul_4341 aldehyde dehydrogenase_; Belongs to the aldehyde dehydrogenase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.911 |
| Bind_0175 | Bind_0041 | Bind_0175 | Bind_0041 | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: xau:Xaut_3248 methylmalonate-semialdehyde dehydrogenase. | PFAM: Aldehyde Dehydrogenase_; KEGG: cak:Caul_4341 aldehyde dehydrogenase_; Belongs to the aldehyde dehydrogenase family. | 0.919 |
| Bind_0175 | Bind_0200 | Bind_0175 | Bind_0200 | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: xau:Xaut_3248 methylmalonate-semialdehyde dehydrogenase. | PFAM: phosphate acetyl/butaryl transferase; KEGG: bch:Bcen2424_4872 phosphate acetyltransferase. | 0.902 |
| Bind_0175 | Bind_0613 | Bind_0175 | Bind_0613 | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: xau:Xaut_3248 methylmalonate-semialdehyde dehydrogenase. | PFAM: AMP-dependent synthetase and ligase; KEGG: dol:Dole_1499 AMP-dependent synthetase and ligase. | 0.911 |
| Bind_0175 | Bind_0618 | Bind_0175 | Bind_0618 | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: xau:Xaut_3248 methylmalonate-semialdehyde dehydrogenase. | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: azc:AZC_0575 methylmalonate-semialdehyde dehydrogenase. | 0.901 |
| Bind_0175 | Bind_0950 | Bind_0175 | Bind_0950 | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: xau:Xaut_3248 methylmalonate-semialdehyde dehydrogenase. | TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: afw:Anae109_2819 quinone oxidoreductase putative YhdH/YhfP. | 0.908 |
| Bind_0175 | Bind_1317 | Bind_0175 | Bind_1317 | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: xau:Xaut_3248 methylmalonate-semialdehyde dehydrogenase. | PFAM: carboxyl transferase; KEGG: ret:RHE_CH02232 propionyl-CoA carboxylase beta chain protein. | 0.919 |
| Bind_0175 | Bind_1318 | Bind_0175 | Bind_1318 | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: xau:Xaut_3248 methylmalonate-semialdehyde dehydrogenase. | PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: azc:AZC_1774 propionyl-coenzyme A carboxylase alpha polypeptide. | 0.904 |
| Bind_0175 | Bind_2202 | Bind_0175 | Bind_2202 | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: xau:Xaut_3248 methylmalonate-semialdehyde dehydrogenase. | PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase; KEGG: azc:AZC_2420 phosphate acetyl/butyryltransferase family protein. | 0.913 |
| Bind_0175 | Bind_2453 | Bind_0175 | Bind_2453 | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: xau:Xaut_3248 methylmalonate-semialdehyde dehydrogenase. | PFAM: phosphate acetyl/butaryl transferase; KEGG: bch:Bcen2424_4872 phosphate acetyltransferase. | 0.902 |
| Bind_0175 | acsA | Bind_0175 | Bind_0053 | TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: xau:Xaut_3248 methylmalonate-semialdehyde dehydrogenase. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.911 |