| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_0846 | Bind_1113 | Bind_0846 | Bind_1113 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: mex:Mext_1947 beta-ketoacyl synthase. | 0.995 |
| Bind_0846 | Bind_1121 | Bind_0846 | Bind_1121 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | PFAM: O-methyltransferase family 2; regulatory protein ArsR; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: azc:AZC_4339 regulatory protein. | 0.604 |
| Bind_0846 | Bind_1123 | Bind_0846 | Bind_1123 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.494 |
| Bind_0846 | Bind_1894 | Bind_0846 | Bind_1894 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; KEGG: ppr:PBPRB0014 hypothetical acyltransferase family protein. | 0.998 |
| Bind_0846 | Bind_2679 | Bind_0846 | Bind_2679 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: spe:Spro_2413 heavy metal translocating P-type ATPase. | 0.587 |
| Bind_0846 | guaB | Bind_0846 | Bind_1923 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.491 |
| Bind_1113 | Bind_0846 | Bind_1113 | Bind_0846 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: mex:Mext_1947 beta-ketoacyl synthase. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.995 |
| Bind_1113 | Bind_1121 | Bind_1113 | Bind_1121 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: mex:Mext_1947 beta-ketoacyl synthase. | PFAM: O-methyltransferase family 2; regulatory protein ArsR; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: azc:AZC_4339 regulatory protein. | 0.561 |
| Bind_1113 | Bind_1123 | Bind_1113 | Bind_1123 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: mex:Mext_1947 beta-ketoacyl synthase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.492 |
| Bind_1113 | Bind_1894 | Bind_1113 | Bind_1894 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: mex:Mext_1947 beta-ketoacyl synthase. | PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; KEGG: ppr:PBPRB0014 hypothetical acyltransferase family protein. | 0.995 |
| Bind_1113 | Bind_2679 | Bind_1113 | Bind_2679 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: mex:Mext_1947 beta-ketoacyl synthase. | Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: spe:Spro_2413 heavy metal translocating P-type ATPase. | 0.532 |
| Bind_1113 | guaB | Bind_1113 | Bind_1923 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: mex:Mext_1947 beta-ketoacyl synthase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.642 |
| Bind_1121 | Bind_0846 | Bind_1121 | Bind_0846 | PFAM: O-methyltransferase family 2; regulatory protein ArsR; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: azc:AZC_4339 regulatory protein. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.604 |
| Bind_1121 | Bind_1113 | Bind_1121 | Bind_1113 | PFAM: O-methyltransferase family 2; regulatory protein ArsR; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: azc:AZC_4339 regulatory protein. | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: mex:Mext_1947 beta-ketoacyl synthase. | 0.561 |
| Bind_1121 | Bind_1122 | Bind_1121 | Bind_1122 | PFAM: O-methyltransferase family 2; regulatory protein ArsR; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: azc:AZC_4339 regulatory protein. | KEGG: xau:Xaut_2831 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.876 |
| Bind_1121 | Bind_1123 | Bind_1121 | Bind_1123 | PFAM: O-methyltransferase family 2; regulatory protein ArsR; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: azc:AZC_4339 regulatory protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.863 |
| Bind_1121 | Bind_1124 | Bind_1121 | Bind_1124 | PFAM: O-methyltransferase family 2; regulatory protein ArsR; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: azc:AZC_4339 regulatory protein. | PFAM: protein of unknown function UPF0047; KEGG: bmu:Bmul_5223 protein of unknown function UPF0047. | 0.780 |
| Bind_1121 | Bind_1642 | Bind_1121 | Bind_1642 | PFAM: O-methyltransferase family 2; regulatory protein ArsR; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: azc:AZC_4339 regulatory protein. | PFAM: ROSMUCR transcriptional regulator; KEGG: azc:AZC_1086 putative transcriptional regulator. | 0.540 |
| Bind_1121 | Bind_1894 | Bind_1121 | Bind_1894 | PFAM: O-methyltransferase family 2; regulatory protein ArsR; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: azc:AZC_4339 regulatory protein. | PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; KEGG: ppr:PBPRB0014 hypothetical acyltransferase family protein. | 0.529 |
| Bind_1121 | Bind_2137 | Bind_1121 | Bind_2137 | PFAM: O-methyltransferase family 2; regulatory protein ArsR; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: azc:AZC_4339 regulatory protein. | TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: oan:Oant_3198 arsenical-resistance protein. | 0.495 |