| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_0147 | Bind_1123 | Bind_0147 | Bind_1123 | KEGG: rpe:RPE_1857 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.422 |
| Bind_0147 | Bind_1137 | Bind_0147 | Bind_1137 | KEGG: rpe:RPE_1857 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: zmo:ZMO0113 para-aminobenzoate synthase component I. | 0.604 |
| Bind_0147 | Bind_1138 | Bind_0147 | Bind_1138 | KEGG: rpe:RPE_1857 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mex:Mext_3906 glutamine amidotransferase of anthranilate synthase. | 0.610 |
| Bind_0147 | Bind_1139 | Bind_0147 | Bind_1139 | KEGG: rpe:RPE_1857 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. | PFAM: aminotransferase class IV; KEGG: mex:Mext_3905 aminotransferase class IV. | 0.717 |
| Bind_0147 | aroB | Bind_0147 | Bind_0354 | KEGG: rpe:RPE_1857 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. | Shikimate kinase., 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.641 |
| Bind_0485 | Bind_1123 | Bind_0485 | Bind_1123 | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: rpa:RPA4607 putative homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.403 |
| Bind_0485 | Bind_1139 | Bind_0485 | Bind_1139 | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: rpa:RPA4607 putative homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | PFAM: aminotransferase class IV; KEGG: mex:Mext_3905 aminotransferase class IV. | 0.587 |
| Bind_0485 | Bind_1913 | Bind_0485 | Bind_1913 | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: rpa:RPA4607 putative homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: bbt:BBta_3501 putative alpha-isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.921 |
| Bind_0485 | aroB | Bind_0485 | Bind_0354 | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: rpa:RPA4607 putative homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Shikimate kinase., 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.401 |
| Bind_0485 | leuA | Bind_0485 | Bind_0596 | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: rpa:RPA4607 putative homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.919 |
| Bind_1123 | Bind_0147 | Bind_1123 | Bind_0147 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: rpe:RPE_1857 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. | 0.422 |
| Bind_1123 | Bind_0485 | Bind_1123 | Bind_0485 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: rpa:RPA4607 putative homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.403 |
| Bind_1123 | Bind_1139 | Bind_1123 | Bind_1139 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: aminotransferase class IV; KEGG: mex:Mext_3905 aminotransferase class IV. | 0.517 |
| Bind_1123 | Bind_1913 | Bind_1123 | Bind_1913 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: bbt:BBta_3501 putative alpha-isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.403 |
| Bind_1123 | aroB | Bind_1123 | Bind_0354 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Shikimate kinase., 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.618 |
| Bind_1123 | leuA | Bind_1123 | Bind_0596 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.403 |
| Bind_1137 | Bind_0147 | Bind_1137 | Bind_0147 | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: zmo:ZMO0113 para-aminobenzoate synthase component I. | KEGG: rpe:RPE_1857 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. | 0.604 |
| Bind_1137 | Bind_1138 | Bind_1137 | Bind_1138 | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: zmo:ZMO0113 para-aminobenzoate synthase component I. | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mex:Mext_3906 glutamine amidotransferase of anthranilate synthase. | 0.999 |
| Bind_1137 | Bind_1139 | Bind_1137 | Bind_1139 | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: zmo:ZMO0113 para-aminobenzoate synthase component I. | PFAM: aminotransferase class IV; KEGG: mex:Mext_3905 aminotransferase class IV. | 0.952 |
| Bind_1137 | Bind_1140 | Bind_1137 | Bind_1140 | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: zmo:ZMO0113 para-aminobenzoate synthase component I. | PFAM: phosphoribosyltransferase; KEGG: nwi:Nwi_0385 phosphoribosyltransferase. | 0.779 |