| node1 | node2 | node1 annotation | node2 annotation | score |
| Bind_1145 | Bind_1146 | PAS/PAC sensor signal transduction histidine kinase; KEGG: azc:AZC_0594 HupT protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: xau:Xaut_0343 NADH ubiquinone oxidoreductase, 20 kDa subunit. | 0.987 |
| Bind_1145 | Bind_1147 | PAS/PAC sensor signal transduction histidine kinase; KEGG: azc:AZC_0594 HupT protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | PFAM: nickel-dependent hydrogenase large subunit; KEGG: azc:AZC_0596 HupV protein; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.985 |
| Bind_1145 | Bind_1148 | PAS/PAC sensor signal transduction histidine kinase; KEGG: azc:AZC_0594 HupT protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.544 |
| Bind_1145 | Bind_1150 | PAS/PAC sensor signal transduction histidine kinase; KEGG: azc:AZC_0594 HupT protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | KEGG: azc:AZC_0598 Ni-Fe hydrogenase small subunit protein; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Nickel-iron dehydrogenase small subunit domain protein. | 0.606 |
| Bind_1145 | Bind_1151 | PAS/PAC sensor signal transduction histidine kinase; KEGG: azc:AZC_0594 HupT protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | PFAM: nickel-dependent hydrogenase large subunit; KEGG: azc:AZC_0599 hydrogenase large subunit protein; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.582 |
| Bind_1145 | Bind_1152 | PAS/PAC sensor signal transduction histidine kinase; KEGG: azc:AZC_0594 HupT protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: azc:AZC_0600 HupC protein. | 0.582 |
| Bind_1145 | Bind_1153 | PAS/PAC sensor signal transduction histidine kinase; KEGG: azc:AZC_0594 HupT protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; PFAM: peptidase M52 hydrogen uptake protein; KEGG: azc:AZC_0601 hydrogen uptake protein. | 0.655 |
| Bind_1145 | Bind_1156 | PAS/PAC sensor signal transduction histidine kinase; KEGG: azc:AZC_0594 HupT protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | PFAM: HupH hydrogenase expression protein; KEGG: xau:Xaut_2179 HupH hydrogenase expression protein. | 0.753 |
| Bind_1145 | Bind_1157 | PAS/PAC sensor signal transduction histidine kinase; KEGG: azc:AZC_0594 HupT protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | PFAM: Rubredoxin-type Fe(Cys)4 protein; KEGG: xau:Xaut_2180 rubredoxin-type Fe(Cys)4 protein. | 0.729 |
| Bind_1145 | Bind_1158 | PAS/PAC sensor signal transduction histidine kinase; KEGG: azc:AZC_0594 HupT protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | KEGG: xau:Xaut_2181 putative hydrogenase expression/formation protein HupK. | 0.959 |
| Bind_1146 | Bind_1145 | PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: xau:Xaut_0343 NADH ubiquinone oxidoreductase, 20 kDa subunit. | PAS/PAC sensor signal transduction histidine kinase; KEGG: azc:AZC_0594 HupT protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | 0.987 |
| Bind_1146 | Bind_1147 | PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: xau:Xaut_0343 NADH ubiquinone oxidoreductase, 20 kDa subunit. | PFAM: nickel-dependent hydrogenase large subunit; KEGG: azc:AZC_0596 HupV protein; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.999 |
| Bind_1146 | Bind_1148 | PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: xau:Xaut_0343 NADH ubiquinone oxidoreductase, 20 kDa subunit. | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.856 |
| Bind_1146 | Bind_1150 | PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: xau:Xaut_0343 NADH ubiquinone oxidoreductase, 20 kDa subunit. | KEGG: azc:AZC_0598 Ni-Fe hydrogenase small subunit protein; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Nickel-iron dehydrogenase small subunit domain protein. | 0.928 |
| Bind_1146 | Bind_1151 | PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: xau:Xaut_0343 NADH ubiquinone oxidoreductase, 20 kDa subunit. | PFAM: nickel-dependent hydrogenase large subunit; KEGG: azc:AZC_0599 hydrogenase large subunit protein; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.996 |
| Bind_1146 | Bind_1152 | PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: xau:Xaut_0343 NADH ubiquinone oxidoreductase, 20 kDa subunit. | TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: azc:AZC_0600 HupC protein. | 0.940 |
| Bind_1146 | Bind_1153 | PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: xau:Xaut_0343 NADH ubiquinone oxidoreductase, 20 kDa subunit. | TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; PFAM: peptidase M52 hydrogen uptake protein; KEGG: azc:AZC_0601 hydrogen uptake protein. | 0.846 |
| Bind_1146 | Bind_1156 | PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: xau:Xaut_0343 NADH ubiquinone oxidoreductase, 20 kDa subunit. | PFAM: HupH hydrogenase expression protein; KEGG: xau:Xaut_2179 HupH hydrogenase expression protein. | 0.887 |
| Bind_1146 | Bind_1157 | PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: xau:Xaut_0343 NADH ubiquinone oxidoreductase, 20 kDa subunit. | PFAM: Rubredoxin-type Fe(Cys)4 protein; KEGG: xau:Xaut_2180 rubredoxin-type Fe(Cys)4 protein. | 0.845 |
| Bind_1146 | Bind_1158 | PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: xau:Xaut_0343 NADH ubiquinone oxidoreductase, 20 kDa subunit. | KEGG: xau:Xaut_2181 putative hydrogenase expression/formation protein HupK. | 0.973 |