Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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Bind_1148(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (779 aa)    
Predicted Functional Partners:
Bind_1164
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: azc:AZC_0612 hydrogenase expression/formation protein.
 
 
 0.983
Bind_1147
PFAM: nickel-dependent hydrogenase large subunit; KEGG: azc:AZC_0596 HupV protein; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 
 0.915
Bind_1163
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: azc:AZC_0611 hydrogenase formation protein; Belongs to the HypD family.
 
  
 0.904
Bind_1162
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: azc:AZC_0610 hydrogenase expression/formation protein.
 
 
 0.901
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.867
Bind_1146
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: xau:Xaut_0343 NADH ubiquinone oxidoreductase, 20 kDa subunit.
 
 
 
 0.856
Bind_1160
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: azc:AZC_0608 hydrogenase accessory protein.
 
   
 0.843
Bind_2478
NADH dehydrogenase (quinone); PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: rle:pRL110293 putative formate hydrogenlyase subunit 5 precursor.
     
 0.610
Bind_0507
PFAM: nickel-dependent hydrogenase large subunit; KEGG: ace:Acel_1019 nickel-dependent hydrogenase, large subunit.
 
   
 0.587
Bind_1145
PAS/PAC sensor signal transduction histidine kinase; KEGG: azc:AZC_0594 HupT protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
       0.544
Your Current Organism:
Beijerinckia indica
NCBI taxonomy Id: 395963
Other names: B. indica subsp. indica ATCC 9039, Beijerinckia indica subsp. indica ATCC 9039, Beijerinckia indica subsp. indica str. ATCC 9039, Beijerinckia indica subsp. indica strain ATCC 9039
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