Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Bind_1179Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (221 aa)    
Predicted Functional Partners:
ccmA
Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 0.999
ccmC
Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.998
ccmE
CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.981
Bind_0709
TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: rpa:RPA0206 putative cytochrome c biogenesis protein, thiol:disulfide interchange protein.
 
  
 0.889
Bind_2232
TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: rpd:RPD_2003 cytochrome c-type biogenesis protein CcmF.
 
  
 0.882
Bind_2233
Cytochrome C biogenesis protein; Possible subunit of a heme lyase.
 
   
 0.843
Bind_2230
KEGG: azc:AZC_1132 cytochrome c-type biogenesis protein; TIGRFAM: cytochrome c-type biogenesis protein CcmI; PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein.
 
   
 0.765
Bind_3369
Gluconate 2-dehydrogenase (acceptor); PFAM: cytochrome c class I; KEGG: cak:Caul_3607 gluconate 2-dehydrogenase (acceptor).
 
   
 0.647
Bind_1181
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
       0.483
Your Current Organism:
Beijerinckia indica
NCBI taxonomy Id: 395963
Other names: B. indica subsp. indica ATCC 9039, Beijerinckia indica subsp. indica ATCC 9039, Beijerinckia indica subsp. indica str. ATCC 9039, Beijerinckia indica subsp. indica strain ATCC 9039
Server load: low (16%) [HD]