| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_0125 | Bind_1209 | Bind_0125 | Bind_1209 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.999 |
| Bind_0125 | Bind_2163 | Bind_0125 | Bind_2163 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.999 |
| Bind_0125 | Bind_2165 | Bind_0125 | Bind_2165 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: rde:RD1_0748 thiamine biosynthesis protein ThiS, putative. | 0.838 |
| Bind_0125 | Bind_2166 | Bind_0125 | Bind_2166 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: mlo:mll5793 thiamine biosynthesis oxidoreductase ThiO. | 0.577 |
| Bind_0125 | Bind_3522 | Bind_0125 | Bind_3522 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | PFAM: thiamine monophosphate synthase; KEGG: rpe:RPE_4721 thiamine monophosphate synthase. | 0.974 |
| Bind_0125 | Bind_3634 | Bind_0125 | Bind_3634 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: mex:Mext_1632 UBA/ThiF-type NAD/FAD binding protein. | 0.774 |
| Bind_0125 | thiC | Bind_0125 | Bind_0063 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.990 |
| Bind_0125 | thiG | Bind_0125 | Bind_2164 | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.925 |
| Bind_1208 | Bind_1209 | Bind_1208 | Bind_1209 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mex:Mext_4238 porphobilinogen synthase; Belongs to the ALAD family. | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.474 |
| Bind_1209 | Bind_0125 | Bind_1209 | Bind_0125 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | KEGG: rle:pRL110441 putative phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.999 |
| Bind_1209 | Bind_1208 | Bind_1209 | Bind_1208 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mex:Mext_4238 porphobilinogen synthase; Belongs to the ALAD family. | 0.474 |
| Bind_1209 | Bind_1778 | Bind_1209 | Bind_1778 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cak:Caul_0933 DEAD/DEAH box helicase domain protein. | 0.491 |
| Bind_1209 | Bind_2163 | Bind_1209 | Bind_2163 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.742 |
| Bind_1209 | Bind_2165 | Bind_1209 | Bind_2165 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: rde:RD1_0748 thiamine biosynthesis protein ThiS, putative. | 0.777 |
| Bind_1209 | Bind_2166 | Bind_1209 | Bind_2166 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: mlo:mll5793 thiamine biosynthesis oxidoreductase ThiO. | 0.588 |
| Bind_1209 | Bind_3522 | Bind_1209 | Bind_3522 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | PFAM: thiamine monophosphate synthase; KEGG: rpe:RPE_4721 thiamine monophosphate synthase. | 0.423 |
| Bind_1209 | Bind_3634 | Bind_1209 | Bind_3634 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: mex:Mext_1632 UBA/ThiF-type NAD/FAD binding protein. | 0.523 |
| Bind_1209 | thiC | Bind_1209 | Bind_0063 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.546 |
| Bind_1209 | thiG | Bind_1209 | Bind_2164 | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.752 |
| Bind_1778 | Bind_1209 | Bind_1778 | Bind_1209 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cak:Caul_0933 DEAD/DEAH box helicase domain protein. | Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.491 |