| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_1178 | Bind_1239 | Bind_1178 | Bind_1239 | PFAM: cyclic nucleotide-binding; MscS Mechanosensitive ion channel; KEGG: rle:pRL110232 putative transmembrane cyclic nucleotide-binding ion channel. | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.595 |
| Bind_1178 | Bind_2679 | Bind_1178 | Bind_2679 | PFAM: cyclic nucleotide-binding; MscS Mechanosensitive ion channel; KEGG: rle:pRL110232 putative transmembrane cyclic nucleotide-binding ion channel. | Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: spe:Spro_2413 heavy metal translocating P-type ATPase. | 0.441 |
| Bind_1178 | guaB | Bind_1178 | Bind_1923 | PFAM: cyclic nucleotide-binding; MscS Mechanosensitive ion channel; KEGG: rle:pRL110232 putative transmembrane cyclic nucleotide-binding ion channel. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.519 |
| Bind_1178 | ribB | Bind_1178 | Bind_0944 | PFAM: cyclic nucleotide-binding; MscS Mechanosensitive ion channel; KEGG: rle:pRL110232 putative transmembrane cyclic nucleotide-binding ion channel. | Transcriptional regulator, XRE family; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.405 |
| Bind_1239 | Bind_1178 | Bind_1239 | Bind_1178 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | PFAM: cyclic nucleotide-binding; MscS Mechanosensitive ion channel; KEGG: rle:pRL110232 putative transmembrane cyclic nucleotide-binding ion channel. | 0.595 |
| Bind_1239 | Bind_1407 | Bind_1239 | Bind_1407 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | PFAM: NAD(P)H dehydrogenase (quinone); KEGG: mlo:mll7814 quinone reductase. | 0.925 |
| Bind_1239 | Bind_1858 | Bind_1239 | Bind_1858 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: ret:RHE_CH00633 putative potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.710 |
| Bind_1239 | Bind_2679 | Bind_1239 | Bind_2679 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: spe:Spro_2413 heavy metal translocating P-type ATPase. | 0.601 |
| Bind_1239 | Bind_2809 | Bind_1239 | Bind_2809 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | PFAM: protein of unknown function DUF1217; KEGG: bov:BOV_A0118 hypothetical protein. | 0.707 |
| Bind_1239 | Bind_2810 | Bind_1239 | Bind_2810 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | KEGG: rpe:RPE_1147 flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family. | 0.707 |
| Bind_1239 | Bind_3653 | Bind_1239 | Bind_3653 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: sme:SMc03030 flagellar basal body rod protein FlgG; Belongs to the flagella basal body rod proteins family. | 0.707 |
| Bind_1239 | guaB | Bind_1239 | Bind_1923 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.640 |
| Bind_1239 | nnrE | Bind_1239 | Bind_2191 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.601 |
| Bind_1239 | ribB | Bind_1239 | Bind_0944 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Transcriptional regulator, XRE family; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.603 |
| Bind_1407 | Bind_1239 | Bind_1407 | Bind_1239 | PFAM: NAD(P)H dehydrogenase (quinone); KEGG: mlo:mll7814 quinone reductase. | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.925 |
| Bind_1407 | Bind_1858 | Bind_1407 | Bind_1858 | PFAM: NAD(P)H dehydrogenase (quinone); KEGG: mlo:mll7814 quinone reductase. | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: ret:RHE_CH00633 putative potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.529 |
| Bind_1858 | Bind_1239 | Bind_1858 | Bind_1239 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: ret:RHE_CH00633 putative potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cak:Caul_4668 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.710 |
| Bind_1858 | Bind_1407 | Bind_1858 | Bind_1407 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: ret:RHE_CH00633 putative potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | PFAM: NAD(P)H dehydrogenase (quinone); KEGG: mlo:mll7814 quinone reductase. | 0.529 |
| Bind_1858 | ribB | Bind_1858 | Bind_0944 | PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: ret:RHE_CH00633 putative potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Transcriptional regulator, XRE family; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.415 |
| Bind_2679 | Bind_1178 | Bind_2679 | Bind_1178 | Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: spe:Spro_2413 heavy metal translocating P-type ATPase. | PFAM: cyclic nucleotide-binding; MscS Mechanosensitive ion channel; KEGG: rle:pRL110232 putative transmembrane cyclic nucleotide-binding ion channel. | 0.441 |