node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bind_0423 | cmk | Bind_0423 | Bind_2938 | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_0205 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | KEGG: xau:Xaut_1111 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | 0.410 |
Bind_0423 | dxr | Bind_0423 | Bind_0297 | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_0205 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.550 |
Bind_0423 | dxs | Bind_0423 | Bind_1811 | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_0205 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.704 |
Bind_0423 | ispDF | Bind_0423 | Bind_1516 | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_0205 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.550 |
Bind_0423 | ispE | Bind_0423 | Bind_0858 | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_0205 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.540 |
Bind_0423 | ispG | Bind_0423 | Bind_0434 | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_0205 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.542 |
Bind_0423 | ispH | Bind_0423 | Bind_1904 | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_0205 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.943 |
Bind_2936 | cmk | Bind_2936 | Bind_2938 | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | KEGG: xau:Xaut_1111 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | 0.950 |
Bind_2936 | ispDF | Bind_2936 | Bind_1516 | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.533 |
Bind_2936 | ispE | Bind_2936 | Bind_0858 | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.425 |
Bind_2936 | ispG | Bind_2936 | Bind_0434 | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.433 |
Bind_2936 | ispH | Bind_2936 | Bind_1904 | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.916 |
cmk | Bind_0423 | Bind_2938 | Bind_0423 | KEGG: xau:Xaut_1111 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_0205 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.410 |
cmk | Bind_2936 | Bind_2938 | Bind_2936 | KEGG: xau:Xaut_1111 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.950 |
cmk | ispDF | Bind_2938 | Bind_1516 | KEGG: xau:Xaut_1111 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.535 |
cmk | ispH | Bind_2938 | Bind_1904 | KEGG: xau:Xaut_1111 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.811 |
dusA | ispH | Bind_0998 | Bind_1904 | TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.698 |
dxr | Bind_0423 | Bind_0297 | Bind_0423 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_0205 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.550 |
dxr | dxs | Bind_0297 | Bind_1811 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.985 |
dxr | ispDF | Bind_0297 | Bind_1516 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.989 |