| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_0267 | Bind_1968 | Bind_0267 | Bind_1968 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | PFAM: response regulator receiver; ANTAR domain protein; KEGG: pat:Patl_2529 response regulator receiver and ANTAR domain protein. | 0.588 |
| Bind_0267 | Bind_1969 | Bind_0267 | Bind_1969 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; flavodoxin/nitric oxide synthase; KEGG: mfa:Mfla_0317 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.878 |
| Bind_0267 | Bind_1970 | Bind_0267 | Bind_1970 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | TIGRFAM: nitrite reductase [NAD(P)H], large subunit; nitrite reductase [NAD(P)H], small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: ppf:Pput_4015 nitrite reductase (NAD(P)H), large subunit. | 0.923 |
| Bind_0267 | Bind_1971 | Bind_0267 | Bind_1971 | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | PFAM: major facilitator superfamily MFS_1; KEGG: eba:ebA1213 nitrate transporter. | 0.633 |
| Bind_0707 | Bind_1968 | Bind_0707 | Bind_1968 | MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; KEGG: rpa:RPA3316 possible chemotaxis CheB/CheR fusion protein; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; HWE histidine kinase; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | PFAM: response regulator receiver; ANTAR domain protein; KEGG: pat:Patl_2529 response regulator receiver and ANTAR domain protein. | 0.564 |
| Bind_0707 | nifH | Bind_0707 | Bind_0473 | MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; KEGG: rpa:RPA3316 possible chemotaxis CheB/CheR fusion protein; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; HWE histidine kinase; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. | 0.400 |
| Bind_0976 | Bind_1968 | Bind_0976 | Bind_1968 | TIGRFAM: urea ABC transporter, urea binding protein; KEGG: azc:AZC_4106 amide-UreA binding protein precursor. | PFAM: response regulator receiver; ANTAR domain protein; KEGG: pat:Patl_2529 response regulator receiver and ANTAR domain protein. | 0.751 |
| Bind_0976 | Bind_1970 | Bind_0976 | Bind_1970 | TIGRFAM: urea ABC transporter, urea binding protein; KEGG: azc:AZC_4106 amide-UreA binding protein precursor. | TIGRFAM: nitrite reductase [NAD(P)H], large subunit; nitrite reductase [NAD(P)H], small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: ppf:Pput_4015 nitrite reductase (NAD(P)H), large subunit. | 0.441 |
| Bind_1967 | Bind_1968 | Bind_1967 | Bind_1968 | ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic component-like protein; KEGG: cyb:CYB_0037 nitrate ABC transporter, ATP-binding protein NtrC. | PFAM: response regulator receiver; ANTAR domain protein; KEGG: pat:Patl_2529 response regulator receiver and ANTAR domain protein. | 0.958 |
| Bind_1967 | Bind_1969 | Bind_1967 | Bind_1969 | ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic component-like protein; KEGG: cyb:CYB_0037 nitrate ABC transporter, ATP-binding protein NtrC. | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; flavodoxin/nitric oxide synthase; KEGG: mfa:Mfla_0317 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.937 |
| Bind_1967 | Bind_1970 | Bind_1967 | Bind_1970 | ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic component-like protein; KEGG: cyb:CYB_0037 nitrate ABC transporter, ATP-binding protein NtrC. | TIGRFAM: nitrite reductase [NAD(P)H], large subunit; nitrite reductase [NAD(P)H], small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: ppf:Pput_4015 nitrite reductase (NAD(P)H), large subunit. | 0.862 |
| Bind_1967 | Bind_1971 | Bind_1967 | Bind_1971 | ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic component-like protein; KEGG: cyb:CYB_0037 nitrate ABC transporter, ATP-binding protein NtrC. | PFAM: major facilitator superfamily MFS_1; KEGG: eba:ebA1213 nitrate transporter. | 0.719 |
| Bind_1968 | Bind_0267 | Bind_1968 | Bind_0267 | PFAM: response regulator receiver; ANTAR domain protein; KEGG: pat:Patl_2529 response regulator receiver and ANTAR domain protein. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.588 |
| Bind_1968 | Bind_0707 | Bind_1968 | Bind_0707 | PFAM: response regulator receiver; ANTAR domain protein; KEGG: pat:Patl_2529 response regulator receiver and ANTAR domain protein. | MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; KEGG: rpa:RPA3316 possible chemotaxis CheB/CheR fusion protein; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; HWE histidine kinase; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | 0.564 |
| Bind_1968 | Bind_0976 | Bind_1968 | Bind_0976 | PFAM: response regulator receiver; ANTAR domain protein; KEGG: pat:Patl_2529 response regulator receiver and ANTAR domain protein. | TIGRFAM: urea ABC transporter, urea binding protein; KEGG: azc:AZC_4106 amide-UreA binding protein precursor. | 0.751 |
| Bind_1968 | Bind_1967 | Bind_1968 | Bind_1967 | PFAM: response regulator receiver; ANTAR domain protein; KEGG: pat:Patl_2529 response regulator receiver and ANTAR domain protein. | ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic component-like protein; KEGG: cyb:CYB_0037 nitrate ABC transporter, ATP-binding protein NtrC. | 0.958 |
| Bind_1968 | Bind_1969 | Bind_1968 | Bind_1969 | PFAM: response regulator receiver; ANTAR domain protein; KEGG: pat:Patl_2529 response regulator receiver and ANTAR domain protein. | PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; flavodoxin/nitric oxide synthase; KEGG: mfa:Mfla_0317 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.903 |
| Bind_1968 | Bind_1970 | Bind_1968 | Bind_1970 | PFAM: response regulator receiver; ANTAR domain protein; KEGG: pat:Patl_2529 response regulator receiver and ANTAR domain protein. | TIGRFAM: nitrite reductase [NAD(P)H], large subunit; nitrite reductase [NAD(P)H], small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: ppf:Pput_4015 nitrite reductase (NAD(P)H), large subunit. | 0.870 |
| Bind_1968 | Bind_1971 | Bind_1968 | Bind_1971 | PFAM: response regulator receiver; ANTAR domain protein; KEGG: pat:Patl_2529 response regulator receiver and ANTAR domain protein. | PFAM: major facilitator superfamily MFS_1; KEGG: eba:ebA1213 nitrate transporter. | 0.658 |
| Bind_1968 | Bind_2628 | Bind_1968 | Bind_2628 | PFAM: response regulator receiver; ANTAR domain protein; KEGG: pat:Patl_2529 response regulator receiver and ANTAR domain protein. | KEGG: xau:Xaut_1352 extracellular ligand-binding receptor. | 0.751 |