| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_0846 | Bind_0855 | Bind_0846 | Bind_0855 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_1373 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.545 |
| Bind_0846 | Bind_1226 | Bind_0846 | Bind_1226 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.618 |
| Bind_0846 | Bind_1405 | Bind_0846 | Bind_1405 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: mex:Mext_3901 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family. | 0.444 |
| Bind_0846 | Bind_1894 | Bind_0846 | Bind_1894 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; KEGG: ppr:PBPRB0014 hypothetical acyltransferase family protein. | 0.998 |
| Bind_0846 | aroB | Bind_0846 | Bind_0354 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | Shikimate kinase., 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.603 |
| Bind_0846 | ubiA | Bind_0846 | Bind_2247 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.608 |
| Bind_0846 | ubiE | Bind_0846 | Bind_2907 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.523 |
| Bind_0846 | ubiG | Bind_0846 | Bind_2011 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.639 |
| Bind_0855 | Bind_0846 | Bind_0855 | Bind_0846 | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_1373 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.545 |
| Bind_0855 | Bind_1405 | Bind_0855 | Bind_1405 | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_1373 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: mex:Mext_3901 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family. | 0.546 |
| Bind_0855 | Bind_1894 | Bind_0855 | Bind_1894 | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_1373 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; KEGG: ppr:PBPRB0014 hypothetical acyltransferase family protein. | 0.487 |
| Bind_0855 | aroB | Bind_0855 | Bind_0354 | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_1373 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Shikimate kinase., 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.542 |
| Bind_0855 | ubiA | Bind_0855 | Bind_2247 | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_1373 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.919 |
| Bind_0855 | ubiE | Bind_0855 | Bind_2907 | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_1373 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.556 |
| Bind_1226 | Bind_0846 | Bind_1226 | Bind_0846 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.618 |
| Bind_1226 | aroB | Bind_1226 | Bind_0354 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Shikimate kinase., 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.447 |
| Bind_1226 | ubiA | Bind_1226 | Bind_2247 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.570 |
| Bind_1226 | ubiG | Bind_1226 | Bind_2011 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.415 |
| Bind_1405 | Bind_0846 | Bind_1405 | Bind_0846 | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: mex:Mext_3901 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; aminotransferase class-III; phosphopantetheine-binding; Beta-ketoacyl synthase; Acyl transferase; KEGG: mes:Meso_2580 amino acid adenylation domain; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.444 |
| Bind_1405 | Bind_0855 | Bind_1405 | Bind_0855 | TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: mex:Mext_3901 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family. | PFAM: Polyprenyl synthetase; KEGG: xau:Xaut_1373 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.546 |