| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_1383 | Bind_2682 | Bind_1383 | Bind_2682 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rpe:RPE_4612 phosphoribosylamine--glycine ligase. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mex:Mext_0996 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.956 |
| Bind_1383 | carB | Bind_1383 | Bind_0869 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rpe:RPE_4612 phosphoribosylamine--glycine ligase. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: azc:AZC_1145 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.462 |
| Bind_1383 | purD | Bind_1383 | Bind_1013 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rpe:RPE_4612 phosphoribosylamine--glycine ligase. | Phosphoribosylamine--glycine ligase; KEGG: btr:Btr_0639 hypothetical protein; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.918 |
| Bind_1383 | purE | Bind_1383 | Bind_0440 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rpe:RPE_4612 phosphoribosylamine--glycine ligase. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
| Bind_1383 | purF | Bind_1383 | Bind_2311 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rpe:RPE_4612 phosphoribosylamine--glycine ligase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.995 |
| Bind_1383 | purH | Bind_1383 | Bind_1287 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rpe:RPE_4612 phosphoribosylamine--glycine ligase. | KEGG: xau:Xaut_1732 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.937 |
| Bind_1383 | purK | Bind_1383 | Bind_0439 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rpe:RPE_4612 phosphoribosylamine--glycine ligase. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.876 |
| Bind_1383 | purL | Bind_1383 | Bind_3119 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rpe:RPE_4612 phosphoribosylamine--glycine ligase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.849 |
| Bind_1383 | purM | Bind_1383 | Bind_1293 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rpe:RPE_4612 phosphoribosylamine--glycine ligase. | KEGG: mex:Mext_2063 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.995 |
| Bind_1383 | purQ | Bind_1383 | Bind_3120 | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rpe:RPE_4612 phosphoribosylamine--glycine ligase. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.882 |
| Bind_2682 | Bind_1383 | Bind_2682 | Bind_1383 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mex:Mext_0996 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: rpe:RPE_4612 phosphoribosylamine--glycine ligase. | 0.956 |
| Bind_2682 | carB | Bind_2682 | Bind_0869 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mex:Mext_0996 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: azc:AZC_1145 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.528 |
| Bind_2682 | purD | Bind_2682 | Bind_1013 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mex:Mext_0996 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylamine--glycine ligase; KEGG: btr:Btr_0639 hypothetical protein; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.968 |
| Bind_2682 | purE | Bind_2682 | Bind_0440 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mex:Mext_0996 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.991 |
| Bind_2682 | purF | Bind_2682 | Bind_2311 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mex:Mext_0996 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.992 |
| Bind_2682 | purH | Bind_2682 | Bind_1287 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mex:Mext_0996 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: xau:Xaut_1732 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.995 |
| Bind_2682 | purK | Bind_2682 | Bind_0439 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mex:Mext_0996 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.991 |
| Bind_2682 | purL | Bind_2682 | Bind_3119 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mex:Mext_0996 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.947 |
| Bind_2682 | purM | Bind_2682 | Bind_1293 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mex:Mext_0996 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: mex:Mext_2063 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. | 0.990 |
| Bind_2682 | purQ | Bind_2682 | Bind_3120 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mex:Mext_0996 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.946 |