| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_0586 | Bind_2350 | Bind_0586 | Bind_2350 | PFAM: Nucleotidyl transferase; KEGG: rpc:RPC_0385 nucleotidyl transferase. | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | 0.502 |
| Bind_2163 | Bind_2350 | Bind_2163 | Bind_2350 | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | 0.605 |
| Bind_2349 | Bind_2350 | Bind_2349 | Bind_2350 | KEGG: acr:Acry_0749 hypothetical protein. | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | 0.614 |
| Bind_2350 | Bind_0586 | Bind_2350 | Bind_0586 | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | PFAM: Nucleotidyl transferase; KEGG: rpc:RPC_0385 nucleotidyl transferase. | 0.502 |
| Bind_2350 | Bind_2163 | Bind_2350 | Bind_2163 | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.605 |
| Bind_2350 | Bind_2349 | Bind_2350 | Bind_2349 | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | KEGG: acr:Acry_0749 hypothetical protein. | 0.614 |
| Bind_2350 | Bind_3041 | Bind_2350 | Bind_3041 | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | PFAM: NLP/P60 protein; KEGG: mex:Mext_0858 NLP/P60 protein. | 0.450 |
| Bind_2350 | Bind_3645 | Bind_2350 | Bind_3645 | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: pap:PSPA7_4208 probable transglycolase. | 0.417 |
| Bind_2350 | anmK | Bind_2350 | Bind_0021 | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.549 |
| Bind_2350 | aroB | Bind_2350 | Bind_0354 | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | Shikimate kinase., 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.439 |
| Bind_3041 | Bind_2350 | Bind_3041 | Bind_2350 | PFAM: NLP/P60 protein; KEGG: mex:Mext_0858 NLP/P60 protein. | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | 0.450 |
| Bind_3645 | Bind_2350 | Bind_3645 | Bind_2350 | TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: pap:PSPA7_4208 probable transglycolase. | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | 0.417 |
| anmK | Bind_2350 | Bind_0021 | Bind_2350 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | 0.549 |
| aroB | Bind_2350 | Bind_0354 | Bind_2350 | Shikimate kinase., 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: mex:Mext_0941 N-acetylmuramoyl-L-alanine amidase family 2. | 0.439 |