| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bind_0812 | Bind_1062 | Bind_0812 | Bind_1062 | KEGG: mex:Mext_2541 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase. | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.919 |
| Bind_0812 | Bind_1123 | Bind_0812 | Bind_1123 | KEGG: mex:Mext_2541 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.962 |
| Bind_0812 | Bind_2455 | Bind_0812 | Bind_2455 | KEGG: mex:Mext_2541 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase. | PFAM: NLPA lipoprotein; KEGG: bmu:Bmul_3391 NlpA lipoprotein; Belongs to the nlpA lipoprotein family. | 0.725 |
| Bind_0812 | Bind_3032 | Bind_0812 | Bind_3032 | KEGG: mex:Mext_2541 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase. | TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pla:Plav_1963 glutamate synthase, NADH/NADPH, small subunit. | 0.705 |
| Bind_0812 | cysC | Bind_0812 | Bind_0070 | KEGG: mex:Mext_2541 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase. | Sulfate adenylyltransferase, large subunit; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.679 |
| Bind_1062 | Bind_0812 | Bind_1062 | Bind_0812 | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | KEGG: mex:Mext_2541 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase. | 0.919 |
| Bind_1062 | Bind_1122 | Bind_1062 | Bind_1122 | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | KEGG: xau:Xaut_2831 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.794 |
| Bind_1062 | Bind_1123 | Bind_1062 | Bind_1123 | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.960 |
| Bind_1062 | Bind_2455 | Bind_1062 | Bind_2455 | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | PFAM: NLPA lipoprotein; KEGG: bmu:Bmul_3391 NlpA lipoprotein; Belongs to the nlpA lipoprotein family. | 0.541 |
| Bind_1062 | cysC | Bind_1062 | Bind_0070 | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Sulfate adenylyltransferase, large subunit; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.442 |
| Bind_1062 | metN | Bind_1062 | Bind_2457 | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | ABC transporter related; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.639 |
| Bind_1122 | Bind_1062 | Bind_1122 | Bind_1062 | KEGG: xau:Xaut_2831 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.794 |
| Bind_1122 | Bind_1123 | Bind_1122 | Bind_1123 | KEGG: xau:Xaut_2831 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
| Bind_1122 | Bind_2455 | Bind_1122 | Bind_2455 | KEGG: xau:Xaut_2831 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | PFAM: NLPA lipoprotein; KEGG: bmu:Bmul_3391 NlpA lipoprotein; Belongs to the nlpA lipoprotein family. | 0.451 |
| Bind_1122 | Bind_2456 | Bind_1122 | Bind_2456 | KEGG: xau:Xaut_2831 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: azc:AZC_3692 putative ABC transporter permease protein. | 0.472 |
| Bind_1122 | cysC | Bind_1122 | Bind_0070 | KEGG: xau:Xaut_2831 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Sulfate adenylyltransferase, large subunit; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.506 |
| Bind_1122 | metN | Bind_1122 | Bind_2457 | KEGG: xau:Xaut_2831 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | ABC transporter related; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.732 |
| Bind_1123 | Bind_0812 | Bind_1123 | Bind_0812 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: mex:Mext_2541 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase. | 0.962 |
| Bind_1123 | Bind_1062 | Bind_1123 | Bind_1062 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: S-adenosylmethionine synthetase; KEGG: azc:AZC_0014 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.960 |
| Bind_1123 | Bind_1122 | Bind_1123 | Bind_1122 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: xau:Xaut_2831 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.999 |