Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bind_2545KEGG: azc:AZC_1865 NADP-dependent isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (405 aa)    
Predicted Functional Partners:
Bind_1181
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.975
Bind_3607
KEGG: xau:Xaut_0156 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; Transketolase central region.
   
 0.968
Bind_2916
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.945
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.930
Bind_1133
KEGG: azc:AZC_1865 NADP-dependent isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
  
 
0.900
Bind_0908
TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: noc:Noc_2707 aconitate hydratase.
  
 0.877
Bind_0775
PFAM: Aldehyde Dehydrogenase_; KEGG: ppu:PP_2488 succinic-semialdehyde dehydrogenase, putative.
   
 0.844
Bind_1820
PFAM: Aldehyde Dehydrogenase_; KEGG: bbt:BBta_3039 putative succinate-semialdehyde dehydrogenase.
   
 0.844
Bind_2831
PFAM: Aldehyde Dehydrogenase_; KEGG: pub:SAR11_0766 succinate-semialdehyde dehydrogenase (NAD(P)); Belongs to the aldehyde dehydrogenase family.
   
 0.844
Bind_3078
PFAM: Aldehyde Dehydrogenase_; KEGG: rso:RS05368 probable ketoglutarate semialdehyde dehydrogenase protein.
   
 0.844
Your Current Organism:
Beijerinckia indica
NCBI taxonomy Id: 395963
Other names: B. indica subsp. indica ATCC 9039, Beijerinckia indica subsp. indica ATCC 9039, Beijerinckia indica subsp. indica str. ATCC 9039, Beijerinckia indica subsp. indica strain ATCC 9039
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