Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Bind_2749KEGG: mex:Mext_3602 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (612 aa)    
Predicted Functional Partners:
Bind_2747
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: atc:AGR_C_4790 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.999
Bind_2751
TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: nwi:Nwi_2798 succinate dehydrogenase, cytochrome b subunit.
 
 0.999
Bind_2750
TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: bme:BMEI0160 succinate dehydrogenase hydrophobic membrane anchor protein.
 
 0.998
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 0.994
Bind_2916
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.990
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.982
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.978
Bind_0775
PFAM: Aldehyde Dehydrogenase_; KEGG: ppu:PP_2488 succinic-semialdehyde dehydrogenase, putative.
   
 0.911
Bind_1820
PFAM: Aldehyde Dehydrogenase_; KEGG: bbt:BBta_3039 putative succinate-semialdehyde dehydrogenase.
   
 0.911
Bind_2831
PFAM: Aldehyde Dehydrogenase_; KEGG: pub:SAR11_0766 succinate-semialdehyde dehydrogenase (NAD(P)); Belongs to the aldehyde dehydrogenase family.
   
 0.911
Your Current Organism:
Beijerinckia indica
NCBI taxonomy Id: 395963
Other names: B. indica subsp. indica ATCC 9039, Beijerinckia indica subsp. indica ATCC 9039, Beijerinckia indica subsp. indica str. ATCC 9039, Beijerinckia indica subsp. indica strain ATCC 9039
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