| node1 | node2 | node1 annotation | node2 annotation | score |
| Bind_1123 | Bind_2985 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: gdi:GDI1519 hypothetical protein. | 0.618 |
| Bind_1123 | Bind_3031 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: xau:Xaut_0477 glutamate synthase (ferredoxin). | 0.451 |
| Bind_1123 | Bind_3157 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: bma:BMAA2099 hypothetical protein. | 0.596 |
| Bind_2985 | Bind_1123 | KEGG: gdi:GDI1519 hypothetical protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.618 |
| Bind_2985 | Bind_3157 | KEGG: gdi:GDI1519 hypothetical protein. | KEGG: bma:BMAA2099 hypothetical protein. | 0.581 |
| Bind_3031 | Bind_1123 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: xau:Xaut_0477 glutamate synthase (ferredoxin). | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.451 |
| Bind_3031 | Bind_3157 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: xau:Xaut_0477 glutamate synthase (ferredoxin). | KEGG: bma:BMAA2099 hypothetical protein. | 0.587 |
| Bind_3152 | Bind_3153 | TIGRFAM: hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: bxe:Bxe_B0022 hypothetical protein. | TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase; KEGG: bja:blr3001 hypothetical protein. | 0.916 |
| Bind_3152 | Bind_3154 | TIGRFAM: hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: bxe:Bxe_B0022 hypothetical protein. | TIGRFAM: squalene synthase HpnD; PFAM: Squalene/phytoene synthase; KEGG: bpd:BURPS668_A3277 squalene/phytoene synthase family protein. | 0.924 |
| Bind_3152 | Bind_3155 | TIGRFAM: hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: bxe:Bxe_B0022 hypothetical protein. | TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mex:Mext_1943 squalene-associated FAD-dependent desaturase. | 0.940 |
| Bind_3152 | Bind_3156 | TIGRFAM: hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: bxe:Bxe_B0022 hypothetical protein. | KEGG: mex:Mext_1944 squalene-hopene cyclase; TIGRFAM: squalene/oxidosqualene cyclase; squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase. | 0.937 |
| Bind_3152 | Bind_3157 | TIGRFAM: hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: bxe:Bxe_B0022 hypothetical protein. | KEGG: bma:BMAA2099 hypothetical protein. | 0.925 |
| Bind_3152 | Bind_3158 | TIGRFAM: hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: bxe:Bxe_B0022 hypothetical protein. | TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM domain protein; KEGG: reh:H16_B2170 predicted Fe-S oxidoreductase. | 0.771 |
| Bind_3152 | Bind_3159 | TIGRFAM: hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: bxe:Bxe_B0022 hypothetical protein. | TIGRFAM: hopanoid biosynthesis associated RND transporter like protein HpnN; KEGG: rpd:RPD_3569 hypothetical protein. | 0.760 |
| Bind_3153 | Bind_3152 | TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase; KEGG: bja:blr3001 hypothetical protein. | TIGRFAM: hopanoid-associated sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: bxe:Bxe_B0022 hypothetical protein. | 0.916 |
| Bind_3153 | Bind_3154 | TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase; KEGG: bja:blr3001 hypothetical protein. | TIGRFAM: squalene synthase HpnD; PFAM: Squalene/phytoene synthase; KEGG: bpd:BURPS668_A3277 squalene/phytoene synthase family protein. | 0.985 |
| Bind_3153 | Bind_3155 | TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase; KEGG: bja:blr3001 hypothetical protein. | TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: mex:Mext_1943 squalene-associated FAD-dependent desaturase. | 0.967 |
| Bind_3153 | Bind_3156 | TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase; KEGG: bja:blr3001 hypothetical protein. | KEGG: mex:Mext_1944 squalene-hopene cyclase; TIGRFAM: squalene/oxidosqualene cyclase; squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase. | 0.922 |
| Bind_3153 | Bind_3157 | TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase; KEGG: bja:blr3001 hypothetical protein. | KEGG: bma:BMAA2099 hypothetical protein. | 0.888 |
| Bind_3153 | Bind_3158 | TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase; KEGG: bja:blr3001 hypothetical protein. | TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM domain protein; KEGG: reh:H16_B2170 predicted Fe-S oxidoreductase. | 0.632 |